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Usefulness of Prostate-Specific Antigen Density as an Indicator for Recommending Prebiopsy Magnetic Resonance Imaging to Prevent Missed Prostate Cancer Diagnoses

Jeon JH, Koo KC, Chung BH, Lee KS

Purpose: To identify the indication for recommending prebiopsy magnetic resonance imaging (MRI) to prevent prostate cancer missed diagnoses in cases without prebiopsy MRI. Materials and Methods: Between January 2017 and September...
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Water-soluble coenzyme Q10 provides better protection than lipid-soluble coenzyme Q10 in a rat model of chronic tacrolimus nephropathy

Cui S, Luo K, Quan Y, Lim SW, Shin YJ, Lee KE, Kim HL, Ko EJ, Kim JH, Chung SJ, Bae SK, Chung BH, Yang CW

Background/Aims: Coenzyme Q10 (CoQ10), is a promising antioxidant; however, low bioavailability owing to lipid-solubility is a limiting factor. We developed water-soluble CoQ10 (CoQ10-W) and compared its effects with conventional lipid-soluble...
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Severe anorexia and weight loss induced by tacrolimus in kidney transplant recipients

Hwang HP, Yu HC, Chung BH, Kang KP, Kim W, Park SK, Lee S

Common neuropsychiatric complications of tacrolimus include tremors, fatigue, headache, sleep disorders, paranoid reactions, and anxiety. Other, more serious complications include encephalopathy, convulsions, confusion, and coma. To our knowledge, however, severe...
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Biomarker for recurrent immunoglobulin A nephropathy in kidney allografts: promising but still a long way to go

Chung BH

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Impact of high body mass index on allograft outcomes in kidney transplant recipients with presensitization to human leukocyte antigen

Park Y, Lee H, Ko EJ, Lee S, Ban TH, Min JW, Yoon HE, Oh EJ, Yang CW, Chung BH

Background: This study aimed to investigate whether high body mass index (BMI) and presensitization to human leukocyte antigen (HLA) in kidney transplant recipients (KTRs) affected allograft outcomes. Methods: From January 2010...
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External Validation of the Long Short-Term Memory Artificial Neural Network-Based SCaP Survival Calculator for Prediction of Prostate Cancer Survival

Lim B, Lee KS, Lee YH, Kim S, Min C, Park JY, Lee HS, Cho JS, Kim SI, Chung BH, Kim CS, Koo KC

Purpose Decision-making for treatment of newly diagnosed prostate cancer (PCa) is complex due to the multiple initial treatment modalities available. We aimed to externally validate the SCaP (Severance Study Group...
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Impact of acute kidney injury in deceased donors with high Kidney Donor Profile Index on posttransplant clinical outcomes: a multicenter cohort study

Park WY, Chang YK, Kim YS, Jin K, Yang CW, Han S, Chung BH

Background: This study evaluated the impact of acute kidney injury (AKI) on posttransplant clinical outcomes for deceased donor (DD) kidney transplantation (KT) using the Kidney Donor Profile Index (KDPI) system....
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Mortality prediction of serum neutrophil gelatinase-associated lipocalin in patients requiring continuous renal replacement therapy

Park Y, Ban TH, Kim HD, Ko EJ, Lee J, Kim SC, Park CW, Yang CW, Kim YS, Chung BH

Background/Aims: We investigated whether serum neutrophil gelatinase-associated lipocalin (NGAL) can predict mortality in patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT). Methods: This study enrolled 169 patients...
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Cellular and genetic signatures of operational tolerance in kidney transplant recipients through single cell RNA sequencing analysis

Bae H, Lee H, Ryu JH, Jang JH, Lee J, Ko GY, Yang CW, Chung BH, Oh EJ

Background: Patients with operational tolerance do not use immunosuppressants after renal transplantation, but they show stable post-transplant results as stable patients with immunosuppressants. We analyzed differently expressed mRNAs and proteins...
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Graft lymphoma in a kidney transplant recipient: a case report

Yeom Jh, Kwon KS, Hwang HP, Yu HC, Chung BH, Park SK, Lee S

Background: Post-transplant lymphoproliferative disorders (PTLDs) are significant complications in solid organ recipients, with various lymphoid and/or plasmacytic proliferations due to immunosuppression. Here, we present the case of pathologically confirmed lymphoma...
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Intra-patient variability in tacrolimus trough levels over 2 years affects long-term allograft outcomes of kidney transplantation

Park Y, Lee H, Eum SH, Kim HD, Ko EJ, Yang CW, Chung BH

Background: The current study aimed to determine the impact of tacrolimus (TAC) trough level (C0) intra-patient variability (IPV) over 2 years after kidney transplantation (KT) on allograft outcomes. Methods: In total,...
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Changing patterns of T lymphocyte subsets after kidney transplantation according to induction immunosuppressant: single center prospective observational study

Kim HD, Bae H, Eum SH, Lee H, Ko EJ, Yang CW, Oh EJ, Chung BH

Background: The aim of this study is to investigate the changing patterns of T cell subsets during early post-transplant period according to the type of induction therapy (anti-thymocyte globulin [ATG]...
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Comparison of the impact between peak mean fluorescent intensity versus sum of mean fluorescent intensity value of donor specific anti-human leukocyte antigen antibody on the posttransplant clinical outcomes

Kim HD, Park Y, Eum SH, Lee H, Ko EJ, Yang CW, Chung BH

Background: In this study, we investigated to verify which of the peak value of donor-specific human leukocyte antigen antibodies (DSA) mean fluorescent intensity (MFI) and sum of MFI had higher...
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Usefulness of BK virus-specific interferon-γ enzyme-linked immunospot assay for predicting the outcome of BK virus infection in kidney transplant recipients

Bae H, Na DH, Chang JY, Park KH, Min JW, Ko EJ, Lee H, Yang CW, Chung BH, Oh EJ

Background/Aims To investigate if BK virus (BKV)-specific T cell immunity measured by an interferon-γ enzyme-linked immunospot (ELISPOT) assay can predict the outcome of BK virus infection in kidney transplant recipients (KTRs). Methods We...
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Relationship between diet quality and sarcopenia in elderly Koreans: 2008–2011 Korea National Health and Nutrition Examination Survey

Na W, Kim J, Chung BH, Jang DJ, Sohn C

BACKGROUND/OBJECTIVES: Given the increasing proportion of the Korean population that is aged 65 years and older, the present study analyzed the relationship between diet quality and sarcopenia in elderly persons...
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Optimal PSA Threshold for Androgen-Deprivation Therapy in Patients with Prostate Cancer following Radical Prostatectomy and Adjuvant Radiation Therapy

Ahn HK, Lee KS, Kim D, Rha KH, Hong SJ, Chung BH, Koo KC

Purpose: The benefits of early administration of androgen-deprivation therapy (ADT) in patients with prostate-specific antigen (PSA)-only recurrent prostate cancer (PCa) following radical prostatectomy (RP) are controversial. We investigated the impact...
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The differential effects of anemia on mortality in young and elderly end-stage renal disease patients

Ko EJ, Kim YK, Cho JH, Kim YS, Kang SW, Kim NH, Kim YL, Yang CW, Chung BH

Background: The aim of this study was to compare the effect of anemia on clinical outcomes according to age in patients with end-stage renal disease (ESRD). Methods: A total of 3,409...
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Recurrent Severe Hyponatremia in a Patient with Sjögren’s Syndrome

Kim HD, Lee J, Chung BH, Yang CW, Kim YS, Park CW

Sjögren's syndrome (SS) is an autoimmune disease that presents with exocrine gland dysfunction. Renal involvement is common in SS and often results in tubulointerstitial nephritis, renal tubular acidosis, and Fanconi’s...
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Development of End Stage Renal Disease after Long-Term Ingestion of Chaga Mushroom: Case Report and Review of Literature

Lee S, Lee HY, Park Y, Ko EJ, Ban TH, Chung BH, Lee HS, Yang CW

Chaga mushrooms are widely used in folk remedies and in alternative medicine. Contrary to many beneficial effects, its adverse effect is rarely reported. We here report a case of end-stage...
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Amyloid light-chain amyloidosis presented as focal segmental glomerulosclerosis in a kidney transplant recipient

Park SH, Kwon SH, Lee HY, Lee S, Ko EJ, Ban TH, Chung BH, Choi YJ, Yang CW

Amyloid light-chain (AL) amyloidosis after kidney transplantation is a rare disease in the world, and only one case of systemic AL amyloidosis after kidney transplantation is reported in Korea. We...
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