Psychiatry Investig.  2011 Mar;8(1):71-73.

Onset of Manic Episode during Chemotherapy with 5-Fluorouracil

Affiliations
  • 1Department of Psychiatry, School of Medicine, Konkuk University, Seoul, Korea. drjaehakyu@yahoo.co.kr
  • 2Department of Surgery, School of Medicine, Konkuk University, Seoul, Korea.

Abstract

The authors report a case of 5-Fluorouracil (5-FU) induced manic episode in an elderly female without any previous psychiatric history. The patient presented manic symptoms after 4th cycle of 5-FU chemotherapy after surgery of rectal cancer. After cessation of chemotherapy and administration of olanzapine and divalproex sodium, symptoms were subsided within 10 days.

Keyword

Manic episode; Colon cancer; 5-FU; Chemotherapy

MeSH Terms

Aged
Benzodiazepines
Colonic Neoplasms
Female
Fluorouracil
Humans
Rectal Neoplasms
Valproic Acid
Benzodiazepines
Fluorouracil
Valproic Acid
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