Pediatr Gastroenterol Hepatol Nutr.  2015 Jun;18(2):115-120. 10.5223/pghn.2015.18.2.115.

Pediatric Cholecystectomy: Clinical Significance of Cases Unrelated to Hematologic Disorders

• Kim HY
• Kim SH
• Cho YH

• KMID: 2315558
• DOI: http://doi.org/10.5223/pghn.2015.18.2.115

Abstract

PURPOSE
Cholecystectomy is rarely performed in the child and adolescent. However, it is associated with several conditions. This study was conducted to describe the characteristics of pediatric patient who underwent cholecystectomy unrelated to hematologic disorders, and then to suggest its clinical significance in management by comparing a simple and complicated gallbladder disease.
METHODS
We reviewed cases of cholecystectomy in pediatric patients (under 18 years old) at a single institution between January 2003 and October 2014. There were 143 cases during the study period and 24 were selected as the subject group.
RESULTS
There were 7 male (29.2%) and 17 female (70.8%) patients. The mean age was 13.1 years old, and 66.6% of patients were older than 12 years. Mean body weight was 52.7 kg, and body mass index was 21.7 kg/m2, with 41.7% of patients being overweight or obese. We could identify a female predominance and high proportion of overweight or obesity in a complicated disease. There were also significantly increased levels of aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP) and bilirubin in this group. Most patients (87.5%) underwent laparoscopic cholecystectomy.
CONCLUSION
Cholecystectomy for diseases unrelated to hematologic disorders is rarely performed in the child and adolescent. In general, female patients who are overweight or obese, and those older than 12 years old, require laparoscopic cholecystectomy owing to multiple gallstones. This condition has a tendency to show a complicated gallbladder disease and significantly increased levels of AST, ALT, ALP, and bilirubin.

Keyword

Cholecystectomy; Child; Adolescent; Female; Overweight; Obesity

MeSH Terms

Adolescent
Alanine Transaminase
Alkaline Phosphatase
Aspartate Aminotransferases
Bilirubin
Body Mass Index
Body Weight
Child
Cholecystectomy*
Cholecystectomy, Laparoscopic
Female
Gallbladder Diseases
Gallstones
Humans
Male
Obesity
Overweight
Alanine Transaminase
Alkaline Phosphatase
Aspartate Aminotransferases
Bilirubin

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