Pediatr Allergy Respir Dis.  2011 Dec;21(4):334-343.

Comparison of Clinical Manifestations of RSV, Rhinovirus and Bocavirus Infections in Children with Acute Wheezing

• Shin HW
• Cho HL
• You JH
• You EJ
• Kim EY
• Kim KS
• Kim YW
• Seo JJ
• Cho HM

Abstract

PURPOSE
The purpose of this study was to compare clinical manifestations of human bocavirus (hBoV), respiratory syncytial virus (RSV), and human rhinovirus (hRV) in children with acute wheezing.
METHODS
We retrospectively investigated 549 virus-positive throat swabs obtained between January 2006 and December 2008 from pediatric inpatients with acute respiratory tract disease at Kwangju Christian Hospital. Among them, 109 patients, who had lower respiratory tract infections with wheezing, were enrolled in this study. The medical records of patients with positive results were reviewed for clinical data.
RESULTS
The mean age of the patients with RSV was 7.15 months, 15.66 months in those with hRV, and 15.04 months in those with hBoV. The mean fever duration and frequency of patients with fever was 2.43 days and 47.9% for RSV, 2.86 days and 51.7% for hRV, and 3.75 days and 69.6% for hBoV. The frequency of patients with acute otitis media was 20.8% in the RSV, 20.7% in the hRV, and 13.0% in the hBoV groups. The frequency of lung infiltration on chest X-ray was 12.5% in the RSV, 20.7% in the hRV, and 47.8% in the hBoV groups.
CONCLUSION
We compared the clinical manifestations of respiratory viral infections in infants and children with wheezing. However, further surveillance will be necessary to clarify the clinical manifestations of the viruses.

Keyword

Bocavirus; RSV; Rhinovirus; Wheezing; Children; Korea

MeSH Terms

Bocavirus
Child
Fever
Human bocavirus
Humans
Infant
Inpatients
Korea
Lung
Medical Records
Otitis Media
Pharynx
Respiratory Sounds
Respiratory Syncytial Viruses
Respiratory Tract Diseases
Respiratory Tract Infections
Retrospective Studies
Rhinovirus
Thorax

Figure

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  Fig. 1. Age distribution of wheezing children infected with respiratory syncytial virus (RSV), human rhinovirus (HRV), human bocavirus (HBoV).

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  Fig. 2. Seasonal distribution of wheezing children infected with respiratory syncytial virus (RSV), human rhinovirus (HRV), human bocavirus (HBoV).

Reference

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