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Asthma predictive index as a useful diagnostic tool in preschool children: a cross-sectional study in Korea

Lee DH, Kwon JW, Kim HY, Seo JH, Kim HB, Lee SY, Jang GC, Song DJ, Kim WK, Jung YH, Hong SJ, Shim JY

Background: It is challenging to diagnose asthma in preschool children. The asthma predictive index (API) has been used to predict asthma and decide whether to initiate treatment in preschool children. Purpose:...
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Exposure to paraben and triclosan and allergic diseases in Tokyo: A pilot cross-sectional study

Mitsui-Iwama M, Yamamoto-Hanada K, Fukutomi Y, Hirota R, Muto G, Nakamura T, Yoshikawa , Nakamura H, Mikami M, Morioka I, Ohya Y

BACKGROUND: Previous studies have reported that exposure to paraben (Pb) and triclosan (TCS) is associated with allergies. However, Pb and TCS exposure in the Japanese population is not fully understood. OBJECTIVES:...
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Biomarkers for Recurrent Wheezing and Asthma in Preschool Children

Lee YJ, Fujisawa T, Kim CK

Wheezing is one of the characteristic symptoms of asthma, but all preschool children with wheezing are not diagnosed with asthma. Preschool children are not cooperative enough to participate in spirometry...
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Comparison of nasal cytokine profiles of human metapneumovirus and respiratory syncytial virus

Park JS, Kim YH, Kwon E, Callaway Z, Fujisawa T, Kim CK

BACKGROUND: Human metapneumovirus (hMPV) and respiratory syncytial virus (RSV) share some epidemiological and clinical characteristics; however, few studies have examined the mechanisms by which these viruses induce airway inflammation. OBJECTIVE: This...
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Clinical characteristics of interferon-gamma-inducible protein of 10 kDa in children with wheezing

Kim BJ, Bae KS, Kim HS, Chun YH, Yoon JS, Kim HH, Kim JT

PURPOSE: Recent studies have shown that interferon-gamma-inducible protein of 10 kDa (IP-10/CXCL10) levels is increased in acute bronchiolitis and asthma. The aim of this study was to examine the levels...
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Prevalence, Severity, and Treatment of Recurrent Wheezing During the First Year of Life: A Cross-Sectional Study of 12,405 Latin American Infants

Mallol J, Sole D, Garcia-Marcos L, Rosario N, Aguirre V, Chong H, Urrutia-Pereira M, Szulman G, Niederbacher J, Arruda-Chavez E, Toledo E, Sanchez L, Pinchak C, EISL Latin American Group

PURPOSE: This study aimed to determine the prevalence and severity of recurrent wheezing (RW) defined as > or =3 episodes of wheezing, risk factors, and treatments prescribed during the first...
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Clinical risk factors associated with the development of wheezing in children less than 2 years of age who required hospitalization for viral lower respiratory tract infections

Kim JH, Choi JY, Kim NY, Kim JW, Baek JH, Baek HS, Yoon JW, Jee HM, Choi SH, Kim HY, Kim KE, Shin YH, Han MY

PURPOSE: Wheezing following viral lower respiratory tract infections (LRTIs) in children
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Factors associated with serum vitamin D levels in children with recurrent wheezing less than 3 years old

Choi EJ, Bag NR, Jung JA, Kim DC, Ahn HS, Yun HJ

PURPOSE: We evaluated the relationship between laboratory/clinical factors and vitamin D levels in recurrent wheezers less than 3 years old. METHODS: We retrospectively analyzed clinical data and laboratory factors (25-hydroxyvitamin D,...
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Association of wheezing phenotypes with fractional exhaled nitric oxide in children

Shim JY

Asthma comprises a heterogeneous group of disorders characterized by airway inflammation, airway obstruction, and airway hyperresponsiveness (AHR). Airway inflammation, which induces AHR and recurrence of asthma, is the main pathophysiology...
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Relationship between breast-feeding and wheeze risk in early childhood in Korean children: based on the fifth Korea National Health and Nutrition Examination Survey 2010-2012

Lee KS, Choi SH, Choi YS, Oh IH, Rha YH

PURPOSE: There is conflicting evidence concerning the relationship between breast-feeding and development of wheezing in early childhood. Epidemiological evidence for a role of breast-feeding on risk of wheezing is inconclusive....
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Effects of wheezing in early childhood in the development of allergic rhinitis in later years

Cetinkaya , Atalay OO

BACKGROUND: Studies on the long-term effects of wheezing in infancy have particularly focused on asthma. There isn't adequate information about the effects of wheezing in the development of allergic rhinitis...
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Factors associated with various clinical manifestations of Mycoplasma pneumonia in children

Kim YN, Park CH, Kim SH, Yoo SJ, Kim HB

PURPOSE: Mycoplasma pneumonia (MP) is a major cause of community-acquired pneumonia in children and young adults. We aimed to investigate the factors that may influence on the clinical manifestations of...
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Early childhood wheezing: various natural courses and their relationship to later asthma

Suh DI, Koh YY

Wheezing is one of the most frequent complaints that lead to the use of medical resources in younger children. Generally, wheezing is caused by bronchiolitis and resolves spontaneously without recurrence,...
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House dust mite sensitization in toddlers predict persistent wheeze in children between eight to fourteen years old

Llanora GV, Ming LJ, Wei LM, van Bever

BACKGROUND: Identifying toddlers at increased risk of developing persistent wheeze provides an opportunity for risk-reducing interventions. House dust mite (HDM) allergen sensitization might identify this group of high-risk children. OBJECTIVE: We...
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The Relationship between the Time of First Respiratory Syncytial Virus Bronchiolitis and Later Wheezing and Asthma Development

Kim RR, Shin MY

  • KMID: 2315211
  • Pediatr Allergy Respir Dis.
  • 2012 Mar;22(1):54-63.
PURPOSE: Respiratory syncytial virus(RSV) bronchiolitis is believed to be associated with later development of asthma and wheezing. This study was conducted to determine the relationship between the age of the...
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Validity of Cough-Holter Monitoring for the Objective Assessment of Cough and Wheezing in Children with Respiratory Symptoms

Park HN, Jang WN, Nam HK, Kang IS, Seo SC, Bauer S, Choi IS, Choung JT, Yoo Y

  • KMID: 2315298
  • Pediatr Allergy Respir Dis.
  • 2012 Dec;22(4):344-353.
PURPOSE: Cough and wheezing are the most common respiratory symptoms in children. Recently, the cough-holter monitoring has been used to estimate the frequency and intensity of cough and wheezing, objectively....
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Infection, eosinophilia and childhood asthma

Kim CK, Callaway Z, Fujisawa T

There is a growing list of viruses and bacteria associated with wheezing illness and asthma. It is well known that a few of these pathogens are strongly associated with wheezing...
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Comparison of Clinical Manifestations of RSV, Rhinovirus and Bocavirus Infections in Children with Acute Wheezing

Shin HW, Cho HL, You JH, You EJ, Kim EY, Kim KS, Kim YW, Seo JJ, Cho HM

  • KMID: 2315160
  • Pediatr Allergy Respir Dis.
  • 2011 Dec;21(4):334-343.
PURPOSE: The purpose of this study was to compare clinical manifestations of human bocavirus (hBoV), respiratory syncytial virus (RSV), and human rhinovirus (hRV) in children with acute wheezing. METHODS: We retrospectively...
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Factors Influencing Recurrent Wheezing in Infants: The Relationship between Respiratory Syncytial Virus Infections and the Development of Recurrent Wheezing

Jung HJ, Kim MJ, Lee K, Kim HJ, Byun SO

  • KMID: 2315158
  • Pediatr Allergy Respir Dis.
  • 2011 Dec;21(4):319-325.
PURPOSE: This study investigated factors affecting recurrent wheezing in infants, focusing on whether or not respiratory syncytial virus (RSV) infections in children
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The Influence of Respiratory Virus and Atopy on Recurrence of Virus Induced Wheezing in Children

Ahn BW, Lee DH, Kang IJ

  • KMID: 2315025
  • Pediatr Allergy Respir Dis.
  • 2010 Sep;20(3):179-187.
PURPOSE: We studied to know the influence of respiratory virus and atopic characteristics on recurrence of virus-induced wheezing in children under 3 years of age. METHODS: Between March 2006 and February...
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