Pediatr Allergy Respir Dis.  2007 Dec;17(4):425-429.

A Case of Chronic Pneumonitis of Infancy in a 3-Year-Old Boy

Affiliations
  • 1Department of Pediatrics, and Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea. mhsohn@yumc.yonsei.ac.kr
  • 2Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Diagnostic Radiology, Yonsei University College of Medicine, Seoul, Korea.
  • 4Department of Diagnostic Pathology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Interstitial lung disease, mostly chronic lung disorder, is usually characterized by diffuse infiltrates and disordered gas exchange, is a very rare disease in children. Chronic pneumonitis of infancy (CPI) is a recently described entity representing a distinct form of interstitial lung disease affecting infants and young children. The histologic findings suggest marked alveolar septal thickening, striking alveolar pneumocyte hyperplasia, and alveolar exudates containing numerous macrophages and foci of eosinophilic debris. A 3-year-old boy visited a local clinic with cough and tachypnea for a duration of 3 weeks. His clinical symptoms were aggravated and he was referred to our hospital. He was diagnosed with chronic pneumonitis of infancy after undergoing open lung biopsy. We herein present the case with review of literature.

Keyword

Chronic pneumonitis of infancy; Interstitial lung disease; Child

MeSH Terms

Biopsy
Child
Child, Preschool*
Cough
Eosinophils
Exudates and Transudates
Humans
Hyperplasia
Infant
Lung
Lung Diseases, Interstitial
Macrophages
Male*
Pneumocytes
Pneumonia*
Rare Diseases
Strikes, Employee
Tachypnea
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