A Case of Allergic Bronchopulmonary Aspergillosis

Yang, In Suk; Kim, Hyun Hee; Kim, So Young; Lee, Won Bae; Lee, Joon Sung

Abstract

Aspergillosis is a systemic fungal infection caused by Aspergilli, mainly, Aspergillus fumigatus. The pulmonary aspergillosis is a group of three separate disease, comprising invasive aspergillosis, aspergilloma, and allergic bronchopulmonary aspergillosis (ABPA), or a disease process in which one of three entities overlap with another process. ABPA is a chracterized clinically by asthma, blood and sputum eosinophilia and recurrent pulmonary infiltrations or mucoid impaction, which pathogenesis seems to be hypersensitivity reaction to Aspergillus fumigatus (Af). Recently we experienced a case of ABPA, one of three clinical manifestations of pulmonary aspergillosis. He had asthma as an infant, but had no asthmatic symptoms on admission, and there was no evidence of fungal infection at blood culture and routine bacterial culture with sputum. But, diagnosis was confirmed by test for immediate skin reaction to Af was positive, skin prick test and Greenburg and Petterson's criteria. After steroid treatment, he became asymptomatic. We report this case with brief review of literature.