Korean J Med.  1999 Jan;56(1):108-112.

A Case of Pulmonary Cryptococcosis diagnosed by Transbronchial Lung Biopsy

Affiliations
  • 1Department of Internal Medcine, College of Medcine, Hallym University, seoul Korea.

Abstract

Cryptococcosis has been considered as an opportunistic mycosis associated with depressed immune function of the host. However, it may develop in healthy individuals without any underlying disease. Recently, we experienced a case of pulmonary cryptococcosis in healthy person. The patient had experienced hemoptysis and dry cough persisted for a month. The chest X-ray and CT showed multifocal pneumonic consolidation containing small cavities in RLL, LUL and LLL. Fiberoptic bronchoscopy didn't revealed endobronchial lesion in both lungs. Transbronchial lung biopsy(TBLB) was done, and we could diagnose pulmonary cryptococcosis by means of histopathologic examination. Clinical evaluations did not reveal immune deficiency or evidence of other specific disease. The patient was treated with fluconazole and resulted in clinical and radiological improvement. Cryptococcosis has well known for its meningeal involvement. Although primary pulmonary cryptococcosis is rare, we must think of it when meet mass or nodular lesion on the chest radiology.

Keyword

Pulmonary cryptococcosis; Healthy person; Transbronchial lung biopsy

MeSH Terms

Biopsy*
Bronchoscopy
Cough
Cryptococcosis*
Fluconazole
Hemoptysis
Humans
Lung*
Thorax
Fluconazole
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