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Subtype-Based Microbial Analysis in Non-small Cell Lung Cancer

Jang HJ, Lee E, Cho YJ, Lee SH

Background: The human lung serves as a niche for a unique and dynamic bacterial community related to the development and aggravation of multiple respiratory diseases. Therefore, identifying the microbiome status...
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Clinical efficacy of angiotensin receptor-neprilysin inhibitor in de novo heart failure with reduced ejection fraction

Park SY, Kong MG, Moon I, Park HW, Choi HO, Seo HS, Cho YH, Lee NH, Lee KY, Jang HJ, Kim JS, Choi IJ, Suh J

Background/Aims: We aimed to analyze the efficacy of angiotensin receptor-neprilysin inhibitor (ARNI) by the disease course of heart failure (HF). Methods: We evaluated 227 patients with HF in a multi-center retrospective...
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Properties of Pleural Mesothelial Cells in Idiopathic Pulmonary Fibrosis and Cryptogenic Organizing Pneumonia

Loloci G, Kim YM, Choi WI, Jang HJ, Park SJ, Kwon KY

Background: Profibrotic properties of pleural mesothelial cells may play an important role in the fibrosis activity in idiopathic pulmonary fibrosis (IPF). The purpose of this study was to compare the...
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Outcomes of the Conventional versus Pocket-Creation Method for Endoscopic Submucosal Dissection of Gastric Body Tumors Using a Dual Knife: A Retrospective Study

Lee SP, Jang HJ, Kae SH, Lee JG

Background/Aims: Various endoscopic submucosal dissection (ESD) methods for gastric tumors have been tried. However, no studies have yet compared results according to the ESD method for gastric body tumors using...
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Advanced In Vitro Three-Dimensional Skin Models of Atopic Dermatitis

Jang HJ, Lee JB, Yoon JK

Atopic dermatitis (AD) is one of the most prevalent inflammatory skin diseases that is characterized by eczematous rashes, intense itching, dry skin, and sensitive skin. Although AD significantly impacts the...
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Associations of Polyp Characteristics in Children and Adolescents Presenting with Less Than Five Colorectal Polyps: A Full Colonoscopy Is Still Required

Kim JY, Kim YB, Choi S, Lee YM, Kim HJ, Kim SC, Jang HJ, Choi SY, Yi DY, Lee Y, Choi YJ, Kang Y, Lee KJ, Hong SJ, Hwang JH, Kwak S, Choe BH, Kang B

Background/Aims: A full colonoscopy is currently required in children and adolescents with colorectal polyps, because of their potential of neoplastic transformation and complications such as intussusception. We aimed to analyze...
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Comparison of safety and efficacy between therapeutic or intermediate versus prophylactic anticoagulation for thrombosis in COVID-19 patients: a systematic review and meta-analysis

Lee HJ, Jang HJ, Choi WI, Joh J, Kim J, Park J, Choi M

Background: Patients with coronavirus disease 2019 (COVID-19) infections often have macrovascular or microvascular thrombosis and inflammation, which are known to be associated with a poor prognosis. Heparin has been hypothesized...
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The Profile of Early Sedation Depth and Clinical Outcomes of Mechanically Ventilated Patients in Korea

Hyun Dg, Ahn JH, Gil HY, Nam CM, Yun C, Lee JM, Kim JH, Lee DH, Kim KH, Kim DJ, Lee SM, Ryu HG, Hong SK, Kim JB, Choi EY, Baek J, Kim J, Kim EJ, Park TY, Kim JH, Park S, Park CM, Jung WJ, Choi NJ, Jang HJ, Lee SH, Lee YS, Suh GY, Choi WS, Lee KS, Kim HW, Min YG, Lee SJ, Lim CM

Background Current international guidelines recommend against deep sedation as it is associated with worse outcomes in the intensive care unit (ICU). However, in Korea the prevalence of deep sedation and its...
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Spontaneous Shrinkage of a Dumbbell-Shaped Schwannoma in the Cervical Spine: A Case Report

Lee SY, Kim KH, Park JY, Chin DK, Kim KS, Cho YE, Jang HJ

Cervical dumbbell-shaped schwannomas are uncommon and challenging; clinicians often face the choice between performing incomplete tumor resection and sacrificing nerve roots. Aggressive and total resection is the treatment of choice...
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Imaging for Screening/Surveillance of Pancreatic Cancer: A Glimpse of Hope

Elbanna KY, Jang HJ, Kim TK

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Relationship between Body Composition and Arterial Stiffness in Korean Adults

Jang HJ, Koh HM, Jang JY, Lee HJ, Moon JS, Ji JM, Lee 1 A

Background: This study is aimed to evaluate the relationship between sarcopenic obesity and atherosclerosis in Korean adults. Methods: We studied 7,177 participants who visited the health promotion center of a university...
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Cancer risk in patients with Peutz-Jeghers syndrome in Korea: a retrospective multi-center study

Kim SH, Kim ER, Park JJ, Kim ES, Goong HJ, Kim KO, Nam JH, Park Y, Lee SP, Jang HJ, KSGE, Research Group of Capsule Endoscopy and Artificial Intelligence in Imaging

Background/Aims: There have been little research on the cancer risks of patients with Peutz-Jeghers syndrome (PJS) in Korea. We aimed to investigate the clinical features of PJS patients and their...
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Safety and Efficacy of Everolimus-Eluting Bioresorbable Vascular Scaffold Versus Second-Generation Drug-Eluting Stents in Real-World Practice

Lee JM, Joh HS, Choi KH, Hong D, Park TK, Yang JH, Song YB, Choi JH, Choi SH, Jeong JO, Lee JY, Choi YJ, Chae JK, Hur SH, Bae JW, Oh JH, Chun KJ, Kim HJ, Cho BR, Shin D, Lee SH, Hwang D, Lee HJ, Jang HJ, Kim HK, Ha SJ, Shin ES, Doh JH, Hahn JY, Gwon HC, on behalf of the SMART-REWARD Investigators

Background: The risk of device thrombosis and device-oriented clinical outcomes with bioresorbable vascular scaffold (BVS) was reported to be significantly higher than with contemporary drug-eluting stents (DESs). However, optimal device...
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Fecal Calprotectin Levels Significantly Correlate with Polyp Size in Children and Adolescents with Juvenile Colorectal Polyps

Kim YB, Kim JY, Choi S, Lee YM, Choi SY, Kim SC, Jang HJ, Lee Y, Jeong IS, Yi DY, Kang Y, Lee KJ, Choe BH, Kang B

Purpose: We aimed to investigate factors that correlate with fecal calprotectin (FC) levels in children and adolescents with colorectal polyps. Methods: Pediatric patients aged
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A case of esophageal perforation caused by suicidal caffeine poisoning in a teenager

Kim SJ, Choi Yj, Lee KS, Jang HJ, Moon JH, Kim YJ, Yang S

Spontaneous esophageal perforation (also known as Boerhaave syndrome) is associated with sudden increase in intra-esophageal pressure by vomiting, coughing or straining at stool. This case describes a 13-year-old girl who...
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Clinical Effect of Transverse Process Hook with K-Means Clustering-Based Stratification of Computed Tomography Hounsfield Unit at Upper Instrumented Vertebra Level in Adult Spinal Deformity Patients

Cho J, Ryu S, Jang HJ, Park JY, Ha Y, Kuh SU, Chin DK, Kim KS, Cho YE, Kim KH

Objective : This study aimed to investigate the efficacy of transverse process (TP) hook system at the upper instrumented vertebra (UIV) for preventing screw pullout in adult spinal deformity surgery...
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Association of Sarcopenia with Heart Rate Variability

Ji JM, Koh HM, Jang JY, Moon JS, Bak HR, Jang HJ, Lee AN, Ko NG

Background: Sarcopenia and decreased heart rate variability (HRV) are reportedly associated with cardiometabolic risk factors. This study aimed to investigate the association between sarcopenia and HRV in patients who visited...
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The free radical scavenger NecroX-7 ameliorates tacrolimusinduced pancreatic β cell dysfunction

Jang HJ, Youn SJ, Oh MY

Background: Tacrolimus (FK506) induces pancreatic beta cell dysfunction, causing new-onset diabetes mellitus after transplan-tation. Cyclopentylamino carboxymethylthiazolylindole (NecroX-7) is a class of indole-derived, cell-permeable, antioxidant mole-cules that exhibit cytoprotective effects in...
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Group 1 metabotropic glutamate receptor 5 is involved in synaptically-induced Ca2+ -spikes and cell death in cultured rat hippocampal neurons

Yang JS, Jeon S, Jang HJ, Yoon SH

Group 1 metabotropic glutamate receptors (mGluRs) can positively affect postsynaptic neuronal excitability and epileptogenesis. The objective of the present study was to determine whether group 1 mGluRs might be involved...
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Comparison of Whole Spine Sagittal Alignment in Patients with Spinal Disease between EOS Imaging System versus Conventional Whole Spine X-ray

Jang HJ, Park JY, Kuh SU, Ha Y, Chin DK, Kim KS, Cho YE, Kim KH

Purpose: The biplanar whole body imaging system (EOS) is a new tool for measuring the whole body sagittal alignment in a limited space. This tool may affect the sagittal balance...
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