Korean J Med.  2001 Jun;60(6):589-592.

A case of slipped capital femoral epiphysis developed during growth hormone treatment

• Kim JE
• Choi YI
• Ha CY
• Lee SJ
• Chung YS
• Lee KW
• Kim HM
• Kim HJ
• Ahn JI

Abstract

Slipped capital femoral epiphysis (SCFE) is the most common orthopedic hip disorder occuring in adolescence. In this condition, the femoral head (epiphysis) displaces, or slips on the femoral neck through the region of the growth plate. This condition can occur only before the epiphyseal plate closes. The exact etiology is unknown, although it has been associated with obesity, hanical abnormalities, physeal abnormalities, endocrine disturbances (hypothyroidism, growth hormone deficiency, hypogonadism). Interestingly, SCFE was observed in growth hormone deficiency and in patients treated with growth hormone. We report a case of an adolescent male with glycogen storage disease Ia and growth hormone deficiency who developed SCFE during treatment with recombinant human growth hormone. A 17-year-old male was admitted for pain of left hip which was exacerbated by walking 15 days ago. He was diagnosed glycogen storage disease Ia and growh hormone deficiency 2 years ago and treated growth hormone therapy with recombinant human growth hormone at the dose of 2 unit/day. The diagnosis of SCFE was confirmed radiologically. From the time of admission, he received skin traction on the left hip joint and stopped to inject growth hormone and treated surgically with internal fixation of the epiphysis with use of 3-cannulated screw. The patient is followed at out-patient clinic without postoperative complication.

Keyword

Epiphyses; Slipped disk; Somatotropin

MeSH Terms

Adolescent
Diagnosis
Epiphyses
Femur Neck
Glycogen Storage Disease
Growth Hormone*
Growth Plate
Head
Hip
Hip Joint
Human Growth Hormone
Humans
Intervertebral Disc Displacement
Male
Obesity
Orthopedics
Outpatients
Postoperative Complications
Skin
Slipped Capital Femoral Epiphyses*
Traction
Walking
Growth Hormone
Human Growth Hormone