Korean J Fam Med.  2010 Jan;31(1):9-15. 10.4082/kjfm.2010.31.1.9.

Association of the Metabolic Syndrome and Bone Mineral Density in Postmenopausal Women

• Park JC
• Kweon HJ
• Oh YK
• Do HJ
• Oh SW
• Lym YL
• Choi JK
• Joh HK
• Cho DY

• KMID: 2304430
• DOI: http://doi.org/10.4082/kjfm.2010.31.1.9

Abstract

BACKGROUND
The metabolic syndrome (MS) is a cluster of risk factors of cardiovascular disease. The association between components of the MS and bone mineral density has been researched, but no prior studies have directly evaluated the association with the metabolic syndrome and bone mineral density in Korea.
METHODS
We evaluated postmenopausal women who had visited a university hospital from November 2006 to October 2007. Data on their lifestyle, current medical diseases and medications were collected from medical records. Height, body weight, waist circumference and serum lipid profiles were measured.
RESULTS
The prevalence of metabolic syndrome was 21.8% in this study. In adjusted analysis including age and other factors, only waist circumference had a close correlation with bone mineral density of femur and lumbar vertebral body (P < 0.05). The bone mineral density of femur and lumbar vertebral body had no correlation with the presence of metabolic syndrome. When stratified by body mass index, corrected bone mineral density revealed no significant correlation with the presence of metabolic syndrome.
CONCLUSION
The bone mineral density of postmenopausal women with metabolic syndrome has highly influenced by obesity, especially by abdominal obesity.

Keyword

Osteoporosis; Bone Mineral Density; Metabolic Syndrome; Abdominal Obesity

MeSH Terms

Body Height
Body Mass Index
Bone Density
Cardiovascular Diseases
Female
Femur
Humans
Life Style
Medical Records
Obesity
Obesity, Abdominal
Osteoporosis
Prevalence
Risk Factors
Waist Circumference