Korean J Dermatol.  2011 Feb;49(2):191-194.

Multiple Merkel Cell Carcinoma in a Vietnam Veteran Exposed to Agent Orange

Affiliations
  • 1Department of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea. smg@dongguk.ac.kr
  • 2Department of Pathology, College of Medicine, Dongguk University, Gyeongju, Korea.

Abstract

Merkel cell carcinoma is a rare aggressive primary skin cancer which mostly occurs in the elderly on sun-exposed skin. It usually presents as a solitary dome-shaped red or purple nodule on the head, neck and extremities. The mortality rate is higher than the rate for malignant melanoma because its local recurrence is common. Agent Orange, an herbicide widely used as a defoliant in the Vietnam War, contains dioxin contaminants and can cause several dermatoses and skin cancers. We report a case of multiple Merkel cell carcinoma in a 65-year-old male with lesions on the head and neck, who had been exposed to Agent Orange during Vietnam War.

Keyword

Agent Orange; Merkel cell carcinoma

MeSH Terms

2,4,5-Trichlorophenoxyacetic Acid
2,4-Dichlorophenoxyacetic Acid
Aged
Carcinoma, Merkel Cell
Citrus sinensis
Extremities
Head
Humans
Male
Melanoma
Neck
Recurrence
Skin
Skin Diseases
Skin Neoplasms
Tetrachlorodibenzodioxin
Veterans
Vietnam
2,4,5-Trichlorophenoxyacetic Acid
2,4-Dichlorophenoxyacetic Acid
Tetrachlorodibenzodioxin
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