Korean J Dermatol.
1999 Apr;37(4):495-499.
The Study of Tenascin Expression in Vitiligo
Abstract
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BACKGROUND: Defective adhesion and migration of melanocyte may be involved in pathogenesis of vitiligo. Tenascin, a glycoprotein of the extracellular matrix, has a role in cell adhesion and migration. It has been reported that abundant expression of tenascin in vitiligo lesion may inhibit melanocyte adhesion and migration.
OBJECTIVE
To investigate the tenascin expression in vitiligo skin lesions and to compare with clinical findings.
METHODS
We studied 9 patients with vitiligo. The expressions of tenascin were studied by immunahistochemieal techniques.
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