Korean J Dermatol.  2005 Jun;43(6):837-839.

A Case of the Sign of Leser-Trelat Associated with Bladder Cancer

Affiliations
  • 1Department of Dermatology, Yonsei University College of Medicine, Wonju, Korea. skahn@wonju.yonsei.ac.kr
  • 2Skin lover Dermatologic Clinic, Korea.

Abstract

The sign of Leser-Trelat refers to the sudden appearance and rapid increase in size and number of seborrheic keratosis. It is considered to be a sign of internal malignant tumors. A 60-year-old male who had received chemotherapy for bladder cancer showed multiple rice to bean-sized dark brownish papules on the scalp and trunk. Skin lesions had suddenly appeared 4 months ago, and he had been diagnosed with transitional cell carcinoma of bladder cancer. The lesions had rapidly increased in number and size. The histopathologic finding of the skin lesions revealed seborrheic keratosis.

Keyword

Leser-Trelat sign; Bladder cancer

MeSH Terms

Carcinoma, Transitional Cell
Drug Therapy
Humans
Keratosis, Seborrheic
Male
Middle Aged
Scalp
Skin
Urinary Bladder Neoplasms*
Urinary Bladder*
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