Korean J Dermatol.
2010 Nov;48(11):1024-1026.
Systemic Lupus Erythematosus That Developed in a Child with Chronic Idiopathic Thrombocytopenic Purpura
- Affiliations
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- 1Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea. dhshin@med.yu.ac.kr
Abstract
- Idiopathic thrombocytopenic purpura (ITP) is a common bleeding disorder in children and it is caused by autoantibodies against platelet surface antigens. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect any part of the body and so result in diverse clinical and laboratory manifestations, including thrombocytopenia. It is known that only 10~15% of all SLE cases are diagnosed during childhood. Thrombocytopenia may be the sole manifestation early in the course of SLE, whereas SLE can subsequently develop in 1~5% of ITP patients. We report here on an interesting case of SLE that developed in an eleven year-old girl with chronic and refractory ITP and who underwent splenectomy.
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