Korean J Dermatol.  2010 Nov;48(11):1020-1023.

A Case of Woringer-Kolopp Disease on the Leg

Affiliations
  • 1Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. woods75@hanmail.net

Abstract

Woringer-Kolopp disease is a rare variant of mycosis fungoides and it is also known as localized pagetoid reticulosis. It presents as a solitary, localized hyperkeratotic patch or plaque on the extremities with a slowly progressive course. A 51-year-old female presented with a 6-year history of a well-defined erythematous plaque with an indurate border on the left leg. The lesion was asymptomatic and it had gradually enlarged. A skin biopsy showed hyperkeratosis and acanthotic epidermis with an infiltration of atypical pagetoid cells, and these cells were revealed to be the cytotoxic T cell phenotype on immunohistochemical staining. We report here on a case of Woringer-Kolopp disease along with a review of the relevant literature.

Keyword

Cutaneous lymphoma; Pagetoid reticulosis; Woringer-Kolopp disease

MeSH Terms

Biopsy
Epidermis
Extremities
Female
Humans
Leg
Middle Aged
Mycosis Fungoides
Pagetoid Reticulosis
Phenotype
Skin
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