Korean J Crit Care Med.  2012 Feb;27(1):24-28. 10.4266/kjccm.2012.27.1.24.

Men Associated with Good Prognosis after Return of Spontaneous Circulation after Out-of Hospital Cardiac Arrest: a Retrospective Study in One Emergency Center

Affiliations
  • 1Department of Emergency Medicine, Gachon University Gil Hospital, Incheon, Korea. empearl@gilhospital.com
  • 2Gachon University of Medicine and Science, Incheon, Korea.
  • 3Department of Emergency Medicine, Samsung Changwon Hospital, Sungkunkwan University College of Medicine, Changwon, Korea.

Abstract

BACKGROUND
The aim of this study was to analyze the gender factors associated with good or bad prognosis after return of spontaneous circulation after out-of hospital cardiac arrest.
METHODS
The patients admitted to the intensive care unit after successful resuscitation after out-of hospital cardiac arrest were retrospectively identified and evaluated. Thirty days mortality after admission, and neurologic outcome at 6 months after hospital discharge (cerebral performance category [CPC]) were evaluated.
RESULTS
One hundred forty-two patients were evaluated in this study; there were 101 males (71.1%). The median age was 52 years old (43-63). Thirty days after admission, 85 patients (59.9%) survived, 40 patients had a good neurologic outcome (CPC 1-2). The factors associated 30 days mortality were cause of arrest (non-cardiac, p = 0.03), lactate in emergency department (p = 0.05) and the factors associated with good neurologic outcome were males (p = 0.007), young age (p = 0.01), body weight and height (p = 0.001), cause of death (cardiac, p = 0.000). Alcohols and smoking were not associated with mortality and neurologic outcome. In multiple logistic regression analysis, men had a 8-fold increased good neurologic outcome (CPC 1-2) (odds ratio [OR] 8.038, 95% Confidence Interval [CI] 1.079-59.903). Other factors associated with good neurologic outcome were cardiac cause of death (OR 5.523, 95% CI 1.562-19.533) and young age (OR 1.055, 95% CI 1.009-1.103).
CONCLUSIONS
Men had a good neurologic outcome after return of spontaneous circulation after out-of hospital cardiac arrest in one emergency center. Other additional factors including gonadal hormones should be evaluated.

Keyword

gender; men; outcome assessment; out-of-hospital cardiac arrest

MeSH Terms

Alcohols
Body Weight
Cause of Death
Emergencies
Gonadal Hormones
Heart Arrest
Humans
Intensive Care Units
Lactic Acid
Logistic Models
Male
Out-of-Hospital Cardiac Arrest
Prognosis
Resuscitation
Retrospective Studies
Smoke
Smoking
Alcohols
Gonadal Hormones
Lactic Acid
Smoke
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