Korean J Asthma Allergy Clin Immunol.  2011 Dec;31(4):295-299.

A Case of Contact Dermatitis Induced by a Petroleum-Based Dry Cleaning Solvent

Abstract

BACKGROUND
Petroleum-based solvents have been widely used for dry cleaning in Korea. Although there has been a few reports of irritant contact dermatitis induced by petroleum-based dry cleaning solvents, this is the first case of contact dermatitis with peripheral eosinophilia in Korea. CASE HISTORY: A 53 year old man had suffered from itching sensation, erythema and bullae in both arms. The onset time was 1 hour after wearing a jacket which had been dry cleaned the day earlier. The skin lesions were localized to the area in contact with the jacket, and the Nikolsky sign was seen. The patient had no history of previous allergic diseases.
RESULTS
Serum total IgE levels, peripheral eosinophil counts, eosinophil cationic protein levels and liver function test results (aspartate and alanine transaminase) were elevated. Histopathological examination of the skin biopsy specimen showed epidermal necrosis with superficial perivenular lymphocytic and eosinophilic infiltration. He was negative for the patch test with maximum 1% of the solvent used at that laundry, which was composed of paraffin and naphten. Therefore, we thought that his skin lesion may be attributed to irritant reactions to this solvent.
CONCLUSION
We report herein a case of contact dermatitis induced by a petroleum-based dry cleaning solvent.


MeSH Terms

Alanine
Arm
Biopsy
Blister
Dermatitis, Contact
Eosinophil Cationic Protein
Eosinophilia
Eosinophils
Erythema
Humans
Immunoglobulin E
Korea
Liver Function Tests
Necrosis
Paraffin
Patch Tests
Petroleum
Pruritus
Sensation
Skin
Solvents
Alanine
Eosinophil Cationic Protein
Immunoglobulin E
Paraffin
Petroleum
Solvents
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