J Korean Acad Child Adolesc Psychiatry.
2014 Mar;25(1):14-19.
Prescribing Patterns for Treatment of Pediatric Bipolar Disorder in a Korean Inpatient Sample
- Affiliations
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- 1Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Children's Hospital, Seoul, Korea. kbn1@snu.ac.kr
Abstract
OBJECTIVES
This study was conducted in order to describe prescribing practices in treatment of pediatric bipolar disorder in a Korean inpatient sample.
METHODS
We performed a retrospective chart review of 66 youths who had been hospitalized and diagnosed with bipolar disorder according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria. Demographics, clinical characteristics, medications used, doses, and related adverse events were examined.
RESULTS
Mood stabilizers and/or atypical antipsychotic medications were the primary treatment. Risperidone, valproate, and lithium were the most commonly used. Thirty seven patients (58.1%) were treated with combination therapy of an atypical antipsychotic and mood stabilizer for improvement of manic/mixed symptoms.
CONCLUSION
Combination pharmacotherapy was necessary for most patients in this admission sample group. Conduct of further studies will be needed for evaluation of treatment response according to the clinical characteristics, and the safety and efficacy of treatment for child and adolescent bipolar disorder.