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Pathological Worry is Related to Poor Long-Term Pharmacological Treatment Response in Patients With Panic Disorder

Kim HJ, Kim JE, Lee SH

Objective Several predictors of unfavorable pharmacological treatment response (PTR) in panic disorder (PD) patients have been suggested, such as the duration of the illness, presence of agoraphobia, depression, being a...
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Korean Medication Algorithm Project for Depressive Disorder 2021 (I): Treatment Strategies for Major Depressive Episode

Woo YS, Bahk WM, Seo JS, Park YM, Kim W, Jeong JH, Shim SH, Lee JG, Jang SH, Wang SM, Jung MH, Sung HM, Choo IH, Yoon BH, Lee SY, Jon DI, Min KJ

Objectives The Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) is a consensus-based medication guideline. To reflect advances in pharmacotherapy for depressive disorders, we have undertaken a fourth revision of...
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Predictors of Remission in Acute and Continuation Treatment of Depressive Disorders

Kim HY, Lee HJ, Jhon M, Kim JW, Kang HJ, Lee JY, Kim SW, Shin IS, Kim JM

Objective: To identify factors predicting remission of depression during acute (12 weeks) and continuation treatment (12 months) using a 1-year, naturalistic prospective study design. Methods: Patients with depressive disorders were recruited...
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Pharmachologic Prophylaxis for Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Choi JH, Lee SH

Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is one of the most burdensome adverse events, occurs in about 3 to 15 percent of patients after the procedure. Various and extensive attempts have...
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Treatment of neuropathic pain

Sohn E

Background: Neuropathic pain presents a therapeutic challenge because patients cannot be relieved from it, even when all known medical options have been tried. Several treatment guidelines have been provided, and...
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Pharmacotherapy for female nocturia

Kim SR

Background: In 2018, nocturia and nocturnal lower urinary tract function definitions were updated in a clinically and practically based consensus report by the International Continence Society Standardization Steering Committee. Previous...
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Early Trauma Is Associated with Poor Pharmacological Treatment Response in Patients with Panic Disorder

Kim HJ, Kim JE, Lee SH

Objective Pharmacotherapy is established as an effective method for reducing symptoms of panic disorder (PD). However, about 20–40% of PD patients are treatment-resistant. Predictors of pharmacotherapy outcomes for PD patients...
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Update on pharmacotherapy for smoking cessation

Choi HS, Kim JY

Cigarette smoking is the leading preventable cause of death, and smoking cessation is the only way to reduce the risk of developing and dying from smoking-related diseases. The binding of...
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Survival, Prognosis, and Clinical Feature of Refractory Myasthenia Gravis: a 15-year Nationwide Cohort Study

Jeong S, Noh Y, Oh IS, Hong YH, Shin JY

Background: Myasthenia gravis (MG) is a rare classic autoimmune disease where immunosuppressant therapies have been successful to reduce MG attributable mortality fairly well. However, patients with refractory MG (rMG) among...
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Pharmacological treatment for attention deficit hyperactivity disorder in adults

Kweon K

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by attention deficits, hyperactivity, and impulsivity. In the past, ADHD was considered to be limited to children and adolescents. However,...
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Update on pharmacotherapy for adult bronchiectasis

Choi H, Lee H, Ra SW, Oh YM

Bronchiectasis refers to abnormal dilatation of the bronchi, which leads to the failure of mucus clearance and increased risk of infection. Pharmacotherapy for stable bronchiectasis includes oral or inhaled mucoactive...
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Recent Advances in the Development of Novel Drug Candidates for Regulating the Secretion of Pulmonary Mucus

Li X, Jin F, Lee HJ, Lee CJ

Hypersecretion of pulmonary mucus is a major pathophysiological feature in allergic and inflammatory respiratory diseases including asthma and chronic obstructive pulmonary disease (COPD). Overproduction and/or oversecretion of mucus cause the...
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Childhood Trauma and Pharmacotherapy Retention among Outpatients with Panic Disorder

Kim DJ, Kim D, Lee J, Kim Y, Sohn S

Objectives:This study investigated lifetime experiences of trauma, treatment retention, and psychiatric symptoms among outpatients with panic disorder after initiation of pharmacotherapy. Our research hypothesis was that panic patients with childhood...
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Pharmacological management of male sexual dysfunction

Yang DY

Male sexual disorders, which are the target of clinical treatment, can be largely divided into erectile dysfunction (ED), ejaculation disorder, infertility, sexual desire disorder, hypogonadism, and other diseases related to...
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Contemporary Pharmacotherapeutics and the Management of Aggressive Behavior in an Adolescent Animal Model of Maladaptive Aggression

Einberger C, Puckett A, Ricci L, Melloni Jr. R

Objective: Antipsychotic and anticonvulsant medications are increasingly being used as pharmacotherapeutic treatments for maladaptive aggression in youth, yet no information is available regarding whether these drugs exhibit aggressionspecific suppression in...
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Management of Osteoporosis in Liver Transplant Recipients

Choi H, Kim B, Kim Y, Lee J, Lee E, Lee E, Cho JY, Choi Y

Background: Prevention of osteoporosis and bone fracture is one of the important issues for liver transplant recipients because a long history of liver disease and lifelong use of immunosuppressants, including...
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Pharmacotherapy for patients with diabetes mellitus

Moon JH, Lim S

Diabetes mellitus (DM) is a complex, chronic illness requiring continuous medical care with multifactorial riskreduction strategies besides glycemic control. The pathophysiology of type 2 DM is characterized by a combination...
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Current status of pulmonary arterial hypertension in Korea

Jang AY, Chung WJ

Pulmonary arterial hypertension (PAH) is characterized by remodeling of the distal pulmonary arteries resulting in high pulmonary vascular resistance and, eventually, right ventricular heart failure. Although current advances in PAH...
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Korean Medication Algorithm for Bipolar Disorder 2018: Comparisons with Other Treatment Guidelines

Jeong JH, Bahk WM, Woo YS, Lee JG, Kim MD, Sohn I, Shim SH, Jon DI, Seo JS, Kim W, Song HR, Min KJ, Yoon BH

The objective of this study was to compare recommendations of the Korean Medication Algorithm Project for Bipolar Disorder 2018 (KMAP-BP 2018) with other recently published guidelines for treating bipolar disorder....
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Natural Products as Sources of Novel Drug Candidates for the Pharmacological Management of Osteoarthritis: A Narrative Review

Kang YH, Lee HJ, Lee CJ, Park JS

Osteoarthritis is a chronic degenerative articular disorder. Formation of bone spurs, synovial inflammation, loss of cartilage, and underlying bone restructuring have been reported to be the main pathologic characteristics of...
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