Korean J Urol.  1989 Dec;30(6):889-894.

Experimental Study of Effects of Water-Soluble Contrast Media on Vas Deferens in Rat Model

Affiliations
  • 1Department of Urology, College of Medicine, Seoul National University, Seoul, Korea.
  • 2Department of Radiology, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

In order to evaluate the effects of injectable agents on the vas deferens, 11 groups of 5 rats(10 vasa deferens) had both vasa deferens injected by vasopuncture with normal saline, methylene blue, 7 water-soluble contract agents and 1 lipid-soluble contrast agent. After 8 weeks, they were compared with the control group for their histologic changes. There were no significantly deteriorating changes in water-soluble agents groups execpt two vasal obstructione resulted from infection. One partial ciliary loss was found in lipid-soluble agent group. In conclusion, vasography with water-solublt agents may be a saft and helpful procedure, which could give us meaningful informations in managing the patients.

Keyword

contrast media; vas deferens

MeSH Terms

Animals
Contrast Media*
Humans
Methylene Blue
Models, Animal*
Rats*
Vas Deferens*
Contrast Media
Methylene Blue
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