Korean J Urol.  1993 Oct;34(5):855-859.

The effect of prazosin as a first-line therapy for the symptomatic benign prostatichypertrophy

• Lee JJ
• Hong SJ

Abstract

We evaluated 41 patients with symptomatic benign prostatic hypertrophy who were treated with prazosin alone more than 3 months. Among them, 21 patients( 51.2%) showed improvement of both symptom score and maximal flow rate. There was the similar effectiveness on the patients with acute urinary retention as on the patients without retention. The pretreated prostate volume and prostate specific antigen were not statistically different between the responders and nonresponders.After with drawl of the medication, almost all patients immediately complained of the symptoms worsened again. So, we concluded that the d-blocker can be used as a first-line therapy in selected patients with symptomatic benign prostatic hypertrophy with temporal effect.

Keyword

Benign prostatic hypertrophy; Prazosin

MeSH Terms

Humans
Prazosin*
Prostate
Prostate-Specific Antigen
Prostatic Hyperplasia
Urinary Retention
Prazosin
Prostate-Specific Antigen