Korean J Thorac Cardiovasc Surg.  2005 Dec;38(12):866-869.

A Case of Pulmonary Langerhans Cell Histiocytosis associated with Central Diabetes Insipidus in Adult: A case report

• Yoo BS
• Lee JW
• Jo TJ
• Hong KW
• Kim KI
• Lee WY
• Kim DG
• Jun SY

Abstract

Langerhans Cell Histiocytosis (LCH) is a pathologic proliferation and infiltration of various organs by Langerhans' cells of unknown cause. Incidence rate of one million parties 3~4 is seen in young child but the incidence is not sure in adult. Organ systems involved by LCH may include skin, ear, bone marrow, liver, spleen, lung, pituitary gland-hypothalamus and GI tracts. In case pituitary-hypothalamus axis are involved, diabetes insipidus happened. Primary Pulmonary Langerhans Cell Histiocytosis(PLCH) with uninvolvement of other organs is rare and accompanied diabetes insipidus is more rare. There are many cases of LCH with diabetes insipidus involve such as central nervous system except lung. PLCH accompany central diabetes insipidus is only 1 case. We report a case of PLCH that accompany central diabetes insipidus with literature investigation inDepartment of Thoracic and Cardiovascular Surgery, Hallym University.

Keyword

Lung neoplasms; Histiocytosis; Diabetes

MeSH Terms

Adult*
Axis, Cervical Vertebra
Bone Marrow
Central Nervous System
Child
Diabetes Insipidus
Diabetes Insipidus, Neurogenic*
Ear
Gastrointestinal Tract
Histiocytosis
Histiocytosis, Langerhans-Cell*
Humans
Incidence
Liver
Lung
Lung Neoplasms
Skin
Spleen