Korean J Thorac Cardiovasc Surg.
2003 Jul;36(7):539-543.
Adult Onset of Langerhans Cell Histiocytosis in the Rib: Report of 2 cases
- Affiliations
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- 1Department of Thoracic and Cardiovascular Surgery, Pochon CHA University, Gumi CHA Hospital, Korea. doa1224@intizen.com
- 2Department of Pathology, Pochon CHA University, Gumi CHA Hospital, Korea.
- 3Department of Radiology, Pochon CHA University, Gumi CHA Hospital, Korea.
Abstract
- Langerhans cell histiocytosis (LCH), previously called histiocytosis X, refers to a spectrum of disease characterized by idiopathic proliferation of histiocytes producing focal or systemic manifestations. Causes and pathogenesis remain unclear. The basic histopatholgic findings are identical in the three well-established clinical syndromes (eosinophilic granuloma, Hand-Shuller-Christian disease, Letterer-Siwe disease). The disease has a predilection for children, although it may occur in adults. We experienced two cases of adult onset Langerhans cell histiocytosis in the ribs. One case was associated with diabetes insipidus and the other case had a solitary lesion.
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