Korean J Psychopharmacol.
2006 Jan;17(1):24-34.
The Feasibility Test of Korean Medication Algorithm for the Treatment with Schizophrenic Patients(I): Analysis Focusing on the Effectiveness of Treatment
- Affiliations
-
- 1Kwangju City Mental Hospital, Kwangju, Korea.
- 2Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea. aym@snu.ac.kr
- 3Institute of Human Behavioral Medicine, Seoul National University College of Medicine, Seoul, Korea.
- 4Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, Korea.
- 5Department of Psychiatry, Yong-In Mental Hospital, Yong-In, Korea.
- 6Department of Psychiatry, College of Medicine, Chung-ang University, Seoul, Korea.
- 7Department of Neuropsychiatry, Korea University College of Medicine, Seoul, Korea.
- 8Department of Psychiatry, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea.
- 9Department of Psychiatry, Sung Kyun Kwan University, KangBuk Samsung Hospital, Seoul, Korea.
- 10Department of Neuropsychiatry, School of Medicine and Institute of Neuroscience, Inje University, Pusan, Korea.
- 11Department of Neuropsychiatry, School of Medicine and The Mental Health Research Institute, Hanyang University, Seoul, Korea.
- 12Department of General Psychiatry, Naju National Hospital, Naju, Korea.
- 13Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.
- 14Bugok National Hospital, Bugok, Korea.
- 15Department of Neuropsychiatry, Our Lady of Mercy Hospital, The Catholic University of Korea, Incheon, Korea.
- 16Department of Neuropsychiatry, Kwangju Severance Psychiatric Hospital, Yonsei University College of Medicine, Gwangju, Korea.
- 17Feasibility of Korean Medication Algorithm for Schizophrenia Project Group, Korea.
Abstract
OBJECTIVES
The Korean College of Neuropsychopharmacology and the Korean Academy of Schizophrenia developed the Korean algorithm project for schizophrenia to aid clinical decisions. The purpose of this study was to assess the feasibility of Korean Medication Algorithm for Schizophrenia patients in clinical settings in Korea.
METHODS
A total of 108 schizophrenia and schizophreniform disorder patients were enrolled at 19 centers and treated according to the algorithm. PANSS (Positive and Negative Symptom Scale) and CGI (Clinical Global Impression) were used to evaluate symptom severity. Also UKU (UKU side effect rating scale) and LUNSERS (Liverpool University Neuroleptic Side Effect Rating Scale), DAI-10 (Drug Attitude Inventory-10), PPS (Patient Preference Scale), SWN (Subjective Well-Being under Neuroleptic treatment) and WHOQOL (World Health Organization Quality of Life) were used to evaluate tolerability and satisfaction of patient respectively.
RESULTS
Overall ratings including symptom severity, compliance of medication, side effect of medication, quality of life were favorable. The treatment response (PANSS improvement > or = 20%) rate was 63%, 75% at the first Clinical decision point (CDP) and 4 month respectively.
CONCLUSION
Symptom improvement, tolerability and quality of life were all favorable. These results suggest that this algorithm can be useful in clinical practices.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- The Feasibility Test of Korean Medication Algorithm for the Treatment with Schizophrenic Patients(III): The Influence of Therapeutic Environment on Application of Korean Medication Algorithm Project for Schizophrenia
- The Feasibility Test of Korean Medication Algorithm for the Treatment with Schizophrenic Patients(IV): Influences of a History of Antipsychotic Treatment on Effectiveness and Algorithm Application
- The Consideration for Revision of the Korean Medication Algorithm for Schizophrenia
- A Comparative Study of Schizophrenic and Medical Inpatients as Informed Drug Consumers
- Designs and Methods for the Development of Korean Medication Algorithm for Schizophrenic Patients
