Korean J Psychopharmacol.  1999 Apr;10(1):95-98.

A Case with the Syndrome of Inappropriate Antidiuretic Hormone Associated with Sertraline

• Lee SH
• Min SK

Abstract

Authors report a case of syndrome of inappropriate antidiuretic hormone(SIADH) associated with sertraline. A 77 years-old male patient showed decreased serum & urine osmolality with symptoms of nausea and anorexia after the ingestion of sertraline, 50 mg for four days, which led to the diagnosis of SIADH. The symptoms of nausea and anorexia improved as serum osmolality improved in several days after discontinuation of sertraline. It is recommended to check serum Na level routinely at the initial treatment when patients on SRRI aggrevate in symptom, have a past history of hyponatremia, or are old.

Keyword

Sertraline; The syndrome of inappropriate antidiuretic hormone(SIADH); Hyponatremia

MeSH Terms

Aged
Anorexia
Diagnosis
Eating
Humans
Hyponatremia
Inappropriate ADH Syndrome
Male
Nausea
Osmolar Concentration
Sertraline*
Sertraline