Korean J Med.
2009 Apr;76(Suppl 1):S158-S163.
The syndrome of inappropriate antidiuretic hormone secretion with olfactory neuroblastoma: A case report
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Inha University, Incheon, Korea. gistmd@gmail.com
- 2Department of Pathology, College of Medicine, Inha University, Incheon, Korea.
- 3Department of Otorhinolaryngology Head and Neck Surgery, College of Medicine, Inha University, Incheon, Korea.
Abstract
- We report a 62-year-old man with histologically confirmed olfactory neuroblastoma who also had the syndrome of inappropriate antidiuretic hormone secretion (SIADH). An olfactory neuroblastoma is a rare malignancy of the nasal cavity or paranasal sinuses and is rarely associated with excess hormone syndromes. The ectopic production of antidiuretic hormone (ADH) by a tumor is most often due to a small cell carcinoma of the lung, while less common causes include an olfactory neuroblastoma. To our knowledge, this is the first reported case of SIADH secondary to an olfactory neuroblastoma in Korea.
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