Korean J Psychopharmacol.
2005 Jul;16(4):285-291.
Feasibility of Korean Medication Algorithm for Bipolar Disorder(II): Choice of Medications
- Affiliations
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- 1Department of Psychiatry, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, Korea.
- 2Department of Psychiatry, College of Medicine, Catholic University, Seoul, Korea. wmbahk@catholic.ac.kr
- 3Department of Psychiatry, Yonsei University College of Medicine, Seoul, Korea.
- 4Department of Neuropsychiatry, College of Medicine, Chung-Ang University, Seoul, Korea.
- 5Naju National Hospital, Naju, Korea.
- 6Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea.
- 7Department of Psychiatry, Ilsan Hospital, National Health Insurance Corporation, Goyang, Korea.
- 8Korean College of Neuropsychopharmacology and Korean Academy of Schizophrenia, Korea.
Abstract
OBJECTIVE
The Korean College of Neuropsychopharmacology and the Korean Academy of Schizophrenia developed the Korean algorithm project for bipolar disorder to aid clinical decisions. The purpose of this study was to investigate the prescribing tendency of psychopharmacological agents such as mood stabilizers and antipsychotics according to the Korean Medication Algorithm for Bipolar Disorder (KMAP-BP) in clinical settings. METHODS: Ninety-two patients were treated according to the algorithm. Among them the selection and dose of drugs were investigated in 71 patients whose precise medication records were available. RESULTS: Lithium (n=37) and divalproex (n=33) were used as mood stabilizers and combination treatment with both medications was done for one patient. Carbamazepine was not used. During the maintenance period, dosage of mood stabilizer was higher for mixed and psychotic mania compared with euphoric mania. Antipsychotic drug was co-administrated with a mood stabilizer from the beginning of the treatment in 62 of 71 patients and risperidone (69.4%) was the most preferred drug. Of those 62 patients who were treated with antipsychotics, 24 patients were initially taking anti-parkinsonian agents. CONCLUSION: This study investigated the prescribing tendency of clinicians who practiced according to the KMAP-BP. Considering the results of this study, further research is needed to revise KMAP-BP.
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