J Asthma Allergy Clin Immunol.
1999 Oct;19(5):720-723.
Occupational asthma induced by ganoderma spores
Abstract
- Occupational asthma induced by the inhalation of the spore of Ganoderma
lucidum was demonstrated in a 43-year-old woman who had cultivated it indoors for
6 years. She had suffered from paroxysmal cough and rarely wheezing dyspnea for two years.
Recently she also had chest tightness and paroxysmal and repeated cough immediately
after the exposure to Ganoderma lucidum spores. Her pulmonary function was normal.
But, her PC20 was 6.4mg/ml in MBPT (methacholine bronchial provocation test).
She showed not only positive reaction to skin prick test but also dual asthmatic
reaction to the bronchial challenge test with antigenic extract of Ganoderma lucidum spores.