Infect Chemother.  2006 Dec;38(6):398-402.

A Case of Cytomegalovirus Enterocolitis and Jejunal Perforation During Immune Reconstitution with Highly Active Antiretroviral Treatment

Affiliations
  • 1Department of Internal Medicine, National Medical Center, Seoul, Korea. sdesdk@kornet.net
  • 2Department of General Surgery, National Medical Center, Seoul, Korea.

Abstract

Immune reconstitution syndrome (IRS) in HIV-infected patients is an adverse consequence of the restoration of pathogen-specific immune responses during the initial months of highly active antiretroviral treatment(HAART). Previously subclinical infections are unmasked or pre-existing opportunistic infections clinically deteriorate as host immunopathological inflammatory responses are switched on. While the eye is the area where Cytomegalovirus(CMV)-associated IRS occurs most often in patients with AIDS, it also can present with intestinal or pulmonary involvement. We present a case report of an HIV-infected patient in whom CMV enterocolitis and jejunal perforation developed after HAART.

Keyword

Cytomegalovirus; Enterocolitis; Immune reconstitution syndrome; Highly active antiretroviral therapy

MeSH Terms

Antiretroviral Therapy, Highly Active
Asymptomatic Infections
Cytomegalovirus*
Enterocolitis*
Humans
Immune Reconstitution Inflammatory Syndrome
Opportunistic Infections
Full Text Links
  • IC
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr