Korean J Pediatr.  2014 Nov;57(11):465-471. 10.3345/kjp.2014.57.11.465.

Current issues of pediatric inflammatory bowel disease in Korea

• Oh SH
• Kim KM

• KMID: 2284133
• DOI: http://doi.org/10.3345/kjp.2014.57.11.465

Abstract

Inflammatory bowel disease (IBD) is a chronic relapsing disorder of unknown etiology, which is believed to be multifactorial. Recently, the incidence of pediatric IBD has steeply increased in Korea since 2000. Poorly controlled disease activity can result in complications such as intestinal fistulae, abscess, and stricture, as well as growth retardation and delayed puberty in children. Because of a lack of confirmative tests, various diagnostic modalities must be used to diagnose IBD. Onset age, location, behavior, and activity are important in selecting treatments. Monogenic IBD must be excluded among infantile and refractory very-early-onset IBD. Early aggressive therapy using biologics has recently been proposed for peripubertal children to prevent growth failure and malnutrition.

Keyword

Inflammatory bowel disease; Child; Crohn disease; Ulcerative colitis

MeSH Terms

Abscess
Age of Onset
Biological Products
Child
Colitis, Ulcerative
Constriction, Pathologic
Crohn Disease
Humans
Incidence
Inflammatory Bowel Diseases*
Intestinal Fistula
Korea
Malnutrition
Puberty, Delayed
Biological Products