Korean J Perinatol.
2011 Jun;22(2):81-87.
Preeclampsia and Innate Immunity
- Affiliations
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- 1Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea. sun3rd@hanmail.net
Abstract
- Preeclampsia(PE) remains a leading cause of maternal and fetal morbidity and mortality. Despite decades of intense research on the problem, there is no early pregnancy screening test to recognize those at risk. Recently, altered immune responses have been suspected to be involved in preeclampsia pathogenesis, which may concern the inflammatory context in which an immune response is mounted. In this review, the innate immunologic pathogenesis of the preeclampsia is reviewed.
