Clin Pediatr Hematol Oncol.  2007 Apr;14(1):93-97.

A Case of Recurrent Growing Teratoma Syndrome during Chemotherapy for Immature Teratoma of the Ovary

Affiliations
  • 1Department of Pediatrics, Chungbuk National University College of Medicine, Cheongju, Korea. jyk@chungbuk.ac.kr
  • 2Department of Pathology, Chungbuk National University College of Medicine, Cheongju, Korea.
  • 3Pediatric Oncology Branch, National Cancer Center, Goyang, Korea.

Abstract

Enlarging masses during or after chemotherapy of malignancy is thought to be the evidence of malignancy recurrence. However, growing teratoma syndrome is defined as enlarging masses of benign mature teratoma following chemotherapy for malignant germ cell tumors. Typically, the histology shows a mature teratoma without any malignant element and it is associated normalization of initially elevated serum tumor markers. We present a case of recurrent growing teratoma syndrome originating from an immature teratoma of the ovary during chemotherapy in a 10-year-old girl.

Keyword

Growing teratoma syndrome; Immature teratoma; Chemotherapy

MeSH Terms

Child
Drug Therapy*
Female
Humans
Neoplasms, Germ Cell and Embryonal
Ovary*
Recurrence
Teratoma*
Biomarkers, Tumor
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