Clin Pediatr Hematol Oncol.  2014 Apr;21(1):33-36.

A Case of Acquired Transient Vitamin K Deficiency in a Teenage Girl

Affiliations
  • 1Department of Pediatrics, Inha University School of Medicine, Incheon, Korea. pedkim@inha.ac.kr
  • 2Department of Laboratory Medicine, Inha University School of Medicine, Incheon, Korea.

Abstract

A 13-year old girl visited emergency medical center presenting with nasal bleeding and gross hematuria. She had no growth retardation, nor history of abnormal bleeding. Her initial blood test results showed normal platelet counts, normal liver enzyme level but prolonged prothrombin time and activated partial thromboplastin time. On admission, she showed massive but intermittent bleeding until the 15th hospital day. Evaluation including coagulation factor assay was done and the results were compatible with vitamin K deficiency. She was treated with vitamin K intramuscular injection 7 times and intermittent transfusion of red blood cells, platelets and fresh frozen plasma. After that, all of her blood test results returned to normal levels including coagulation tests concomitent with resolving symptoms. In that there were no proof of underlying diseases that can cause vitamin K deficiency, she was diagnosed as idiopathic transient vitamin K deficiency.

Keyword

Vitamin K deficiency; Idiopathic; Adolescent

MeSH Terms

Adolescent
Blood Coagulation Factors
Emergencies
Epistaxis
Erythrocytes
Female
Hematologic Tests
Hematuria
Hemorrhage
Humans
Injections, Intramuscular
Liver
Partial Thromboplastin Time
Plasma
Platelet Count
Prothrombin Time
Vitamin K
Vitamin K Deficiency*
Blood Coagulation Factors
Vitamin K
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