Clin Pediatr Hematol Oncol.
2014 Oct;21(2):135-139. 10.0000/cpho.2014.21.2.135.
A Case of Childhood Paroxysmal Cold Hemoglobinuria Related with Suspicious Chlamydia Infection
- Affiliations
-
- 1Center for Pediatric Oncology, Department of Laboratory Medicine, National Cancer Center, Goyang, Korea. hjpark@ncc.re.kr
- 2Center for Diagnostic Oncology, Department of Laboratory Medicine, National Cancer Center, Goyang, Korea.
- 3Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea.
- KMID: 2279823
- DOI: http://doi.org/10.0000/cpho.2014.21.2.135
Abstract
- Paroxysmal cold hemoglobinuria (PCH) is a rare diagnosis of acquired hemolytic anemia in children, which is caused by a specific cold antibody named Donath-Landsteiner hemolysin. Although various bacteria or viruses were reported as triggering factor of PCH, childhood PCH related to Chlamydia pneumoniae infection is uncommon. The authors report a case of childhood PCH which is related with suspicious Chlamydia pneumoniae infection, with a review of pertinent literature.
