Clin Nutr Res.  2013 Jul;2(2):154-158. 10.7762/cnr.2013.2.2.154.

Changes in Dietary Intake, Body Weight, Nutritional Status, and Metabolic Rate in a Pancreatic Cancer Patient

Affiliations
  • 1Department of Clinical Nutrition, National Cancer Center, Goyang 410-769, Korea.
  • 2Center for Liver Cancer, National Cancer Center, Goyang 410-769, Korea. wsm@ncc.re.kr

Abstract

Pancreatic cancer patients often have a poor prognosis and suffer from nutritional problems. Malnutrition is characterized by weight loss and decreased dietary intake, and is common among pancreatic cancer patients. The objective of this report was to describe the changes in dietary intake, body weight, nutritional status, and metabolic rate on a continuum from the time of diagnosis until the end of life in a patient with pancreatic cancer. In summary, the patient's nutritional status gradually declined, accompanied by extreme weight loss and decreased dietary intake. Conversely, resting energy expenditure, measured by indirect calorimetry, increased from 24 kcal/kg/day to 35 kcal/kg/day. Nutritional management during cancer treatment is important but may be challenging in pancreatic cancer patients.

Keyword

Pancreatic cancer; Diet records; Nutritional status; Basal metabolism

MeSH Terms

Basal Metabolism
Body Weight*
Calorimetry, Indirect
Diagnosis
Diet Records
Energy Metabolism
Humans
Malnutrition
Nutritional Status*
Pancreatic Neoplasms*
Prognosis
Weight Loss

Reference

1. Stan SD, Singh SV, Brand RE. Chemoprevention strategies for pancreatic cancer. Nat Rev Gastroenterol Hepatol. 2010; 7:347–356.
Article
2. Bye A, Jordhøy MS, Skjegstad G, Ledsaak O, Iversen PO, Hjermstad MJ. Symptoms in advanced pancreatic cancer are of importance for energy intake. Support Care Cancer. 2013; 21:219–227.
Article
3. Wigmore SJ, Plester CE, Richardson RA, Fearon KC. Changes in nutritional status associated with unresectable pancreatic cancer. Br J Cancer. 1997; 75:106–109.
Article
4. Okusaka T, Okada S, Ishii H, Ikeda M, Kosakamoto H, Yoshimori M. Prognosis of advanced pancreatic cancer patients with reference to calorie intake. Nutr Cancer. 1998; 32:55–58.
Article
5. Ferrucci LM, Bell D, Thornton J, Black G, McCorkle R, Heimburger DC, Saif MW. Nutritional status of patients with locally advanced pancreatic cancer: a pilot study. Support Care Cancer. 2011; 19:1729–1734.
Article
6. Davidson W, Ash S, Capra S, Bauer J. Cancer Cachexia Study Group. Weight stabilisation is associated with improved survival duration and quality of life in unresectable pancreatic cancer. Clin Nutr. 2004; 23:239–247.
Article
7. Bosaeus I, Daneryd P, Svanberg E, Lundholm K. Dietary intake and resting energy expenditure in relation to weight loss in unselected cancer patients. Int J Cancer. 2001; 93:380–383.
Article
8. Elliott L, Molseed LL, McCallum PD. The clinical guide to oncology nutrition. 2nd ed. Chicago (IL): American Dietetic Association;2006.
9. Bauer J, Reeves MM, Capra S. The agreement between measured and predicted resting energy expenditure in patients with pancreatic cancer: a pilot study. JOP. 2004; 5:32–40.
10. Falconer JS, Fearon KC, Plester CE, Ross JA, Carter DC. Cytokines, the acute-phase response, and resting energy expenditure in cachectic patients with pancreatic cancer. Ann Surg. 1994; 219:325–331.
Article
11. Barber MD, McMillan DC, Preston T, Ross JA, Fearon KC. Metabolic response to feeding in weight-losing pancreatic cancer patients and its modulation by a fish-oil-enriched nutritional supplement. Clin Sci (Lond). 2000; 98:389–399.
Article
12. Dempsey DT, Feurer ID, Knox LS, Crosby LO, Buzby GP, Mullen JL. Energy expenditure in malnourished gastrointestinal cancer patients. Cancer. 1984; 53:1265–1273.
Article
13. Vaisman N, Lusthaus M, Niv E, Santo E, Shacham-Shmueli E, Geva R, Figer A. Effect of tumor load on energy expenditure in patients with pancreatic cancer. Pancreas. 2012; 41:230–232.
Article
14. Woo SM, Joo J, Lee WJ, Park SJ, Han SS, Kim TH, Koh YH, Kim HB, Hong EK. Risk of pancreatic cancer in relation to ABO blood group and hepatitis C virus infection in Korea: a case-control study. J Korean Med Sci. 2013; 28:247–251.
Article
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