Clin Exp Otorhinolaryngol.  2013 Jun;6(2):73-77.

Effects of Rhinophototherapy on Quality of Life in Persistant Allergic Rhinitis

• Tatar EC
• Korkmaz H
• Surenoglu
• Saylam G
• Ozdek A

Abstract

OBJECTIVES
To investigate the effect of rhinophototherapy with medical therapy on quality of life in persistent allergic rhinitis.
METHODS
A prospective, randomized study was being performed between December 2009 and March 2010. The study included 65 patients with persistent allergic rhinitis. The diagnosis was confirmed with positive skin tests. All of the patients had house dust mite allergies. We divided the patients into two groups. First group (n=33) was given topical mometasone furoate 200 mcg/day and levocetirizine 5 mg/day for a month. Rhinophototherapy was applied with the same medical therapy to the second group (n=32), twice a week for three weeks continuously. Rhinophototherapy included visible light, ultraviolet A and ultraviolet B. We evaluated patients before the treatment, at the first month and at the third month after treatment with rhinoconjunctivitis quality of life questionnaire, nasal symptom scores and visual analogue scale (VAS) scores.
RESULTS
Improvements of all variables of the quality of life questionnaire, nasal symptom scores and VAS were statistically significant in the second group both on the first and the third months when compared with the first group.
CONCLUSION
Allergic rhinitis is a social problem and impairs quality of life. Rhinophototherapy with medical therapy improves the quality of life in allergic rhinitis.

Keyword

Allergic rhinitis; Rhinophototherapy; Quality of life; Symptoms scores; Visual analogue scale

MeSH Terms

Cetirizine
Humans
Hypersensitivity
Light
Pregnadienediols
Prospective Studies
Pyroglyphidae
Quality of Life
Rhinitis
Rhinitis, Allergic, Perennial
Skin Tests
Social Problems
Mometasone Furoate
Surveys and Questionnaires
Cetirizine
Pregnadienediols

Reference

1. Oettgen HC, Geha RS. IgE in asthma and atopy: cellular and molecular connections. J Clin Invest. 1999; 10. 104(7):829–835. PMID: 10510320.

2. Weber RW. Allergic rhinitis. Prim Care. 2008; 3. 35(1):1–10. PMID: 18206714.

3. Kay AB. Allergy and allergic diseases: second of two parts. N Engl J Med. 2001; 1. 344(2):109–113. PMID: 11150362.

4. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy. 2008; 4. 63(Suppl 86):8–160. PMID: 18331513.

5. Krouse JH. Allergic rhinitis: current pharmacotherapy. Otolaryngol Clin North Am. 2008; 4. 41(2):347–358. PMID: 18328373.

6. Ferguson BJ. Environmental controls of allergies. Otolaryngol Clin North Am. 2008; 4. 41(2):411–417. PMID: 18328378.

7. Ahmad N, Zacharek MA. Allergic rhinitis and rhinosinusitis. Otolaryngol Clin North Am. 2008; 4. 41(2):267–281. PMID: 18328367.

8. Calderon MA, Casale TB, Togias A, Bousquet J, Durham SR, Demoly P. Allergen-specific immunotherapy for respiratory allergies: from meta-analysis to registration and beyond. J Allergy Clin Immunol. 2011; 1. 127(1):30–38. PMID: 20965551.

9. Man LX. Complementary and alternative medicine for allergic rhinitis. Curr Opin Otolaryngol Head Neck Surg. 2009; 6. 17(3):226–231. PMID: 19262383.

10. Csoma Z, Koreck A, Ignacz F, Bor Z, Szabo G, Bodai L, et al. PUVA treatment of the nasal cavity improves the clinical symptoms of allergic rhinitis and inhibits the immediate-type hypersensitivity reaction in the skin. J Photochem Photobiol B. 2006; 4. 83(1):21–26. PMID: 16406552.

11. Csoma Z, Ignacz F, Bor Z, Szabo G, Bodai L, Dobozy A, et al. Intranasal irradiation with the xenon chloride ultraviolet B laser improves allergic rhinitis. J Photochem Photobiol B. 2004; 9. 75(3):137–144. PMID: 15341927.

12. Koreck AI, Csoma Z, Bodai L, Ignacz F, Kenderessy AS, Kadocsa E, et al. Rhinophototherapy: a new therapeutic tool for the management of allergic rhinitis. J Allergy Clin Immunol. 2005; 3. 115(3):541–547. PMID: 15753902.

13. Cingi C, Cakli H, Yaz A, Songu M, Bal C. Phototherapy for allergic rhinitis: a prospective, randomized, single-blind, placebo-controlled study. Ther Adv Respir Dis. 2010; 8. 4(4):209–213. PMID: 20587541.

14. Kemeny L, Koreck A. Ultraviolet light phototherapy for allergic rhinitis. J Photochem Photobiol B. 2007; 4. 87(1):58–65. PMID: 17329119.

15. Koreck A, Csoma Z, Boros-Gyevi M, Ignacz F, Bodai L, Dobozy A, et al. Inhibition of immediate type hypersensitivity reaction by combined irradiation with ultraviolet and visible light. J Photochem Photobiol B. 2004; 12. 77(1-3):93–96. PMID: 15542366.

16. Cingi C, Yaz A, Cakli H, Ozudogru E, Kecik C, Bal C. The effects of phototherapy on quality of life in allergic rhinitis cases. Eur Arch Otorhinolaryngol. 2009; 12. 266(12):1903–1908. PMID: 19626333.

17. Garaczi E, Boros-Gyevi M, Bella Z, Csoma Z, Kemeny L, Koreck A. Intranasal phototherapy is more effective than fexofenadine hydrochloride in the treatment of seasonal allergic rhinitis: results of a pilot study. Photochem Photobiol. 2011; Mar-Apr. 87(2):474–477. PMID: 21366599.

18. Mitchell D, Paniker L, Sanchez G, Bella Z, Garaczi E, Szell M, et al. Molecular response of nasal mucosa to therapeutic exposure to broad-band ultraviolet radiation. J Cell Mol Med. 2010; 1. 14(1-2):313–322. PMID: 18671762.

19. Koreck A, Szechenyi A, Morocz M, Cimpean A, Bella Z, Garaczi E, et al. Effects of intranasal phototherapy on nasal mucosa in patients with allergic rhinitis. J Photochem Photobiol B. 2007; 12. 89(2-3):163–169. PMID: 17997323.