- Epithelial PI3K-δ Promotes House Dust Mite-Induced Allergic Asthma in NLRP3 Inflammasome-Dependent and -Independent Manners
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Kim SR, Park HJ, Lee KB, Kim HJ, Jeong JS, Cho SH, Lee YC
- KMID: 2468466
- Allergy Asthma Immunol Res.
- 2020 Mar;12(2):338-358.
- doi: 10.4168/aair.2020.12.2.338
PURPOSE: Phosphoinositide 3-kinase (PI3K)-δ-dependent Akt activation is known to play critical roles in various immune responses of white blood cells in which PI3K-δ isoform is mostly expressed in contrast to... -
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- Optimization of Allergen Panels for Diagnosis of Allergic Rhinitis
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Lee J, Kim JK, Kim KS, Rhee CS
- KMID: 2466708
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2019 Nov;62(11):609-616.
- doi: 10.3342/kjorl-hns.2019.00451
The selection of allergen panel is very important to test for innumerable allergens throughout the Korea. However, the allergens studied are heterogeneous depending on the area the patient live and... -
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- Safety of Ultra-rush Schedule of Subcutaneous Allergen Immunotherapy With House Dust Mite Extract Conducted in an Outpatient Clinic in Patients With Atopic Dermatitis and Allergic Rhinitis
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Lee SH, Kim ME, Shin YS, Ye YM, Park HS, Nahm DH
- KMID: 2459188
- Allergy Asthma Immunol Res.
- 2019 Nov;11(6):846-855.
- doi: 10.4168/aair.2019.11.6.846
PURPOSE: Ultra-rush schedule of subcutaneous allergen immunotherapy (UR-SCIT) administering maximum maintenance dose of allergen extract within one day can save time and effort for allergen immunotherapy in patients with allergic... -
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- Recent changing pattern of aeroallergen sensitization in children with allergic diseases: A single center study
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Lee SJ, Kim JM, Kim HB
- KMID: 2461395
- Allergy Asthma Respir Dis.
- 2019 Oct;7(4):186-191.
- doi: 10.4168/aard.2019.7.4.186
PURPOSE: Allergic diseases have been increasing worldwide over the past few decades. Allergic sensitization is a pivotal risk factor for the development of allergic diseases. The purpose of this study... -
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- Profiling of remote skeletal muscle gene changes resulting from stimulation of atopic dermatitis disease in NC/Nga mouse model
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Lee D, Seo Y, Kim YW, Kim S, Choi J, Moon SH, Bae H, Kim HS, Kim H, Kim JH, Kim TY, Kim E, Yim S, Lim I, Bang H, Kim JH, Ko JH
- KMID: 2455813
- Korean J Physiol Pharmacol.
- 2019 Sep;23(5):367-379.
- doi: 10.4196/kjpp.2019.23.5.367
Although atopic dermatitis (AD) is known to be a representative skin disorder, it also affects the systemic immune response. In a recent study, myoblasts were shown to be involved in... -
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- Effects of Vacuuming Mattresses on Allergic Rhinitis Symptoms in Children
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Jeon YH, Lee YJ, Sohn MH, Lee HR
- KMID: 2452756
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):655-663.
- doi: 10.4168/aair.2019.11.5.655
PURPOSE: To evaluate the effects of daily vacuuming of mattresses on the concentration of house dust mite (HDM) allergens and on allergic rhinitis (AR) symptoms in children sensitized to HDM. METHODS:... -
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- Survey of IgE Reactivity to Nonbiting Midges in Korea and Identification of IgE-Binding Protein
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Yi MH, Kim JY, Jeong KY, Ree HI, Yong TS
- KMID: 2452755
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):644-654.
- doi: 10.4168/aair.2019.11.5.644
PURPOSE: Chironomids (nonbiting midges) are widely and abundantly distributed near ponds, rivers, and artificially dammed pools used for irrigation. Chironomids contain allergens and cause airway allergy in humans. In this... -
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- House Dust Mite Allergy Under Changing Environments
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Acevedo N, Zakzuk J, Caraballo
- KMID: 2448749
- Allergy Asthma Immunol Res.
- 2019 Jul;11(4):450-469.
- doi: 10.4168/aair.2019.11.4.450
Environmental variations induced by industrialization and climate change partially explain the increase in prevalence and severity of allergic disease. One possible mechanism is the increase in allergen production leading to... -
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- Factors Associated with Adherence to Allergen Specific Subcutaneous Immunotherapy
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Lee JH, Lee SH, Ban GY, Ye YM, Nahm DH, Park HS, Shin YS
- KMID: 2446963
- Yonsei Med J.
- 2019 Jun;60(6):570-577.
- doi: 10.3349/ymj.2019.60.6.570
PURPOSE: Allergen-specific immunotherapy (AIT) is known to be the only therapeutic modality to alter the natural course of allergic diseases. However, at least 3 years of treatment is recommended for... -
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- Clinical Characteristics and Genetic Variations in Early-Onset Atopic Dermatitis Patients
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Kim BJ, Wang HY, Lee H, Lee SY, Hong SJ, Choi EH
- KMID: 2444860
- Ann Dermatol.
- 2019 Jun;31(3):286-293.
- doi: 10.5021/ad.2019.31.3.286
BACKGROUND: Hereditary factors contribute to atopic dermatitis (AD) development. We developed the reverse blot hybridization assay (REBA) kit to simultaneously detect variations in skin barrier- and immune response-related genes prevalent... -
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- Validation of PROTIA™ Allergy-Q 64 Atopy® as a Specific IgE Measurement Assay for 10 Major Allergen Components
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Kim SR, Park KH, Lee JH, Kim BJ, Hwang JH, Lim KJ, Park JW
- KMID: 2442052
- Allergy Asthma Immunol Res.
- 2019 May;11(3):422-432.
- doi: 10.4168/aair.2019.11.3.422
PURPOSE: Component-resolved diagnostics (CRD) is expected to provide additional diagnostic information in allergic patients. PROTIA™ Allergy-Q 64 Atopy®, a recently developed CRD-based multiplex specific immunoglobulin E (sIgE) assay, can quantitatively... -
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- Altered Sphingolipid Metabolism Is Associated With Asthma Phenotype in House Dust Mite-Allergic Patients
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Kowal K, Żebrowska E, Chabowski
- KMID: 2442045
- Allergy Asthma Immunol Res.
- 2019 May;11(3):330-342.
- doi: 10.4168/aair.2019.11.3.330
PURPOSE: Sphingolipids play an important role in cell growth, survival, inflammation and tissue remodeling. House dust mite (HDM) allergy is a major risk factor for asthma. The aim of the... -
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- The prevalence of allergic diseases in school children of metropolitan city in Indonesia shows a similar pattern to that of developed countries
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Soegiarto , Abdullah M, Damayanti , Suseno A, Effendi C
- KMID: 2444117
- Asia Pac Allergy.
- 2019 Apr;9(2):e17.
- doi: 10.5415/apallergy.2019.9.e17
BACKGROUND: The prevalence of allergy among Surabaya school children is currently unknown. OBJECTIVE: To identify the prevalence of the common allergic sensitization and allergic diseases among school children and undergraduate students... -
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- A Fusion Protein of Derp2 Allergen and Flagellin Suppresses Experimental Allergic Asthma
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Tan W, Zheng JH, Duong TM, Koh YI, Lee SE, Rhee JH
- KMID: 2431857
- Allergy Asthma Immunol Res.
- 2019 Mar;11(2):254-266.
- doi: 10.4168/aair.2019.11.2.254
PURPOSE: The house dust mite (HDM) is one of the most important sources of indoor allergens and a significant cause of allergic rhinitis and allergic asthma. Our previous studies demonstrated... -
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- A case of anhidrotic ectodermal dysplasia presenting with pyrexia, atopic eczema, and food allergy
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Suzuki T, Tajima H, Migita M, Pawankar R, Yanagihara T, Fujita A, Shima Y, Yanai E, Katsube Y
- KMID: 2433664
- Asia Pac Allergy.
- 2019 Jan;9(1):e3.
- doi: 10.5415/apallergy.2019.9.e3
Anhidrotic ectodermal dysplasia (AED) is a rare hereditary disorder with a triad of sparse hair, dental hypoplasia, and anhidrosis. Here we report a case of AED with food allergy and... -
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- Effects of Ser47-Point Mutation on Conformation Structure and Allergenicity of the Allergen of Der p 2, a Major House Dust Mite Allergen
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Kulwanich , Thanyaratsrisakul S, Jirapongsananuruk O, Hales BJ, Thomas WR, Piboonpocanun S
- KMID: 2426791
- Allergy Asthma Immunol Res.
- 2019 Jan;11(1):129-142.
- doi: 10.4168/aair.2019.11.1.129
PURPOSE: Hypoallergenic recombinant Der p 2 has been produced by various genetic manipulations, but mutation of a naturally polymorphic amino acid residue known to affect IgE binding has not been... -
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- Comparison of Long-term Efficacy of Subcutaneous Immunotherapy in Pediatric and Adult Patients With Allergic Rhinitis
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Huang Y, Wang C, Cao F, Zhao Y, Lou H, Zhang L
- KMID: 2426786
- Allergy Asthma Immunol Res.
- 2019 Jan;11(1):68-78.
- doi: 10.4168/aair.2019.11.1.68
PURPOSE: Data comparing the long-term efficacy and safety of subcutaneous immunotherapy (SCIT) using house dust mite (HDM) in children and adults with allergic rhinitis (AR) are limited. This study aimed... -
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- Montelukast Reduces Serum Levels of Eosinophil-Derived Neurotoxin in Preschool Asthma
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Kim CK, Callaway Z, Park JS, Nishimori , Ogino T, Nagao M, Fujisawa T
- KMID: 2441817
- Allergy Asthma Immunol Res.
- 2018 Nov;10(6):686-697.
- doi: 10.4168/aair.2018.10.6.686
PURPOSE: Several markers for eosinophilic inflammation have been proposed to predict response to asthma treatment. However, definitive criteria for treatment decisions have not yet been established. We investigate a potentially... -
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- Efficacy and Safety of Sublingual Immunotherapy in Elderly Rhinitis Patients Sensitized to House Dust Mites
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Kim JH, Lee JH, Ye YM, Lee JH, Park JW, Hur GY, Kim JH, Lee HY, Shin YS, Yang EM, Park HS
- KMID: 2441816
- Allergy Asthma Immunol Res.
- 2018 Nov;10(6):675-685.
- doi: 10.4168/aair.2018.10.6.675
PURPOSE: This study aims to determine the efficacy and safety of house dust mite (HDM)-sublingual immunotherapy (SLIT) in elderly patients with AR. METHODS: A total of 45 patients aged ≥ 60... -
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- Decreased CRTH2 Expression and Response to Allergen Re-stimulation on Innate Lymphoid Cells in Patients With Allergen-Specific Immunotherapy
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Mitthamsiri W, Pradubpongsa P, Sangasapaviliya A, Boonpiyathad T
- KMID: 2441815
- Allergy Asthma Immunol Res.
- 2018 Nov;10(6):662-674.
- doi: 10.4168/aair.2018.10.6.662
PURPOSE: Group 2 innate lymphoid cells (ILC2s) have been implicated in the pathogenesis of allergic disease. However, the effect of allergen-specific immunotherapy (AIT) on ILCs remains to be clarified. The... -
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