Korean J Obstet Gynecol.  2012 Dec;55(12):935-939. 10.5468/KJOG.2012.55.12.935.

Serum anti-Mullerian hormone levels in the patients with ovarian endometriosis undergoing surgical treatment

• Lee JR
• Lee MY
• Park HW
• Cha SW
• Park CW
• Kim JY
• Yang KM
• Song IO
• Koong MK
• Kang IS
• Kim HO

• KMID: 2274200
• DOI: http://doi.org/10.5468/KJOG.2012.55.12.935

Abstract

OBJECTIVE
To evaluate the difference of serumanti-Mullerian hormone (AMH) levels in women between undergoing previous ovarian surgery with endometriosis and controls.
METHODS
We reviewed medical records and evaluated the serum AMH levels of 217 women (26-40 years old) between March 2010 and January 2011, retrospectively. One hundred five patients were previously undergone the ovarian surgery of endometriosis (study group) and 112 women has never undergone ovarian surgery as controls (control group). Exclusion criteria was following factors: irregular menstruation, polycystic ovary syndrome, high BMI (> or =30 kg/m2), other endocrine disease.
RESULTS
The mean age in study group was not different with control group (32.5 +/- 3.6 vs. 33.0 +/- 3.8 year). The mean serum AMH levels significantly lower in the study group than in control (2.82 +/- 2.4 ng/mL vs. 3.82 +/- 2.8 ng/mL, P=0.005). When we analyzed the serum AMH levels according to age groups, the patients above 31 years showed significantly lower levels than control (31-35 years, 2.41+/-1.7 ng/mL vs. 3.84 +/- 2.6 ng/mL, P=0.005; 36-40 years, 1.36 +/- 2.0 ng/mL vs. 2.68 +/- 2.7 ng/mL, P=0.018) The serum AMH levels didn't show any statistical difference in aspect of bilaterality, endometriosis stage, cyst size (> or =6 cm).
CONCLUSION
We could consider relatively low serum AMH levels in patients with ovarian endometriosis after surgical treatment.

Keyword

Anti-Mullerian hormone; Ovarian endometriosis; Endometriosis; Ovarian reserve

MeSH Terms

Anti-Mullerian Hormone
Endometriosis
Female
Humans
Medical Records
Menstruation
Polycystic Ovary Syndrome
Retrospective Studies
Anti-Mullerian Hormone

Figure

• 

  Fig. 1 Serum anti-Müllerian hormone (AMH) concentration between study group and control group according to the age. Values are median (lines), 25-75th percentiles (boxes) and 95% confidence interval (whiskers). aP = 0.005, bP = 0.018.

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