J Menopausal Med.
2020 Aug;26(2):143-146. 10.6118/jmm.20004.
Two Cases of Primary Ovarian Insufficiency Accompanied by High Serum Anti-Müllerian Hormone Levels and Preservation of Ovarian Follicles
- Affiliations
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- 1Department of Obstetrics and Gynecology, Inje University Haeundae Paik Hospital, Busan, Korea
- 2Busan Maria Fertility Clinic, Busan, Korea
- 3Department of Obstetrics and Gynecology, Pusan National University Yangsan Hospital, Yangsan, Korea
- KMID: 2505711
- DOI: http://doi.org/10.6118/jmm.20004
Abstract
- Primary ovarian insufficiency (POI) is defined as the presence of amenorrhea for ≥ 4 months accompanied by evidence of two serum follicle-stimulating hormone levels in the menopausal range in women aged < 40 years. Anti-Müllerian hormone (AMH) has been recognized as the most reliable marker of ovarian reserve status, and its serum level is very low or undetectable in women with POI. Here we report two cases of patients who were diagnosed with POI despite high serum AMH levels and preservation of ovarian follicles, as revealed by ultrasound. In addition, we have presented a review of the current literature regarding this condition.
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