Clin Exp Reprod Med.  2014 Jun;41(2):86-91. 10.5653/cerm.2014.41.2.86.

Serum luteinizing hormone level and luteinizing hormone/follicle-stimulating hormone ratio but not serum anti-Mullerian hormone level is related to ovarian volume in Korean women with polycystic ovary syndrome

• Chun S

• KMID: 2049070
• DOI: http://doi.org/10.5653/cerm.2014.41.2.86

Abstract

OBJECTIVE
The aim of the present study was to investigate the relationship between ovarian follicle count and volume on ultrasonography and serum hormone levels including the levels of the anti-Mullerian hormone (AMH) and gonadotropin in women with the polycystic ovary syndrome (PCOS).
METHODS
A total of 118 Korean women aged 18-35 years who were newly diagnosed with PCOS at a university hospital were included in this study. Serum LH, FSH, and AMH levels were measured in the early follicular phase, and the total antral follicle count (TFC) and the total ovarian volume (TOV) were assessed by ultrasonography. The correlations between serum hormonal parameters and ultrasonography characteristics in women with PCOS were evaluated using Pearson's correlation coefficients and a linear regression analysis.
RESULTS
Serum AMH levels were significantly correlated with serum LH levels and LH/FSH ratios, and TFC and TOV were significantly correlated with each other on ultrasonography. Serum AMH and LH levels and the LH/FSH ratio were significantly correlated with TFC. Statistically significant correlations between TOV and the LH level (r=0.208, p=0.024) and the LH/FSH ratio (r=0.237, p=0.010) were observed. However, the serum AMH level was not significantly correlated with the ovarian volume, and this result did not change after adjusting for age and body mass index.
CONCLUSION
Serum AMH is not related to the ovarian volume in women with PCOS. My results suggest that serum LH level and the LH/FSH ratio may be more useful than the serum AMH level for representing the status of the ovarian volume in women with PCOS.

Keyword

Anti-Mullerian hormone; Luteinizing hormone; Luteinizing hormone/follicle-stimulating hormone ratio; Ovarian volume; Polycystic ovary syndrome

MeSH Terms

Anti-Mullerian Hormone*
Body Mass Index
Female
Follicular Phase
Gonadotropins
Humans
Linear Models
Lutein*
Luteinizing Hormone*
Ovarian Follicle
Polycystic Ovary Syndrome*
Ultrasonography
Anti-Mullerian Hormone
Gonadotropins
Lutein
Luteinizing Hormone