J Menopausal Med.  2023 Dec;29(3):127-133. 10.6118/jmm.23024.

Initial Preoperative Hemoglobin Level Affects the Rate of Decline in Anti-Müllerian Hormone Levels after Laparoscopic Ovarian Cystectomy in Women with Ovarian Endometriosis

• Rhee S
• Chun S
• Ji YI

• KMID: 2550646
• DOI: http://doi.org/10.6118/jmm.23024

Abstract

Objectives
To determine the factors affecting the decline in ovarian reserve following laparoscopic ovarian cystectomy (LOC) in women with ovarian endometriosis.
Methods
This retrospective study included 22 women, aged 25–45 years, with regular menstrual cycles who underwent unilateral LOC and were diagnosed with ovarian endometriosis at a university hospital. Blood samples were collected preoperatively and on the third postoperative day to determine the serum anti-Müllerian hormone (AMH) levels for assessment of the decline in ovarian reserve during the early postoperative period.
Results
The preoperative hemoglobin level, white blood cell count, and AMH level were associated with changes in the AMH level after unilateral LOC. Among these parameters, only the preoperative hemoglobin level was correlated with the rate of decline in postoperative AMH levels. The preoperative serum AMH level was correlated with the amount of postoperative AMH change but not with its rate of decline.
Conclusions
Preoperative hemoglobin levels may be associated with the rate of decline in AMH levels in the early postoperative period after unilateral LOC.

Keyword

Anti-Müllerian hormone; Endometriosis; Hemoglobins; Laparoscopic ovarian cystectomy