Korean J Obstet Gynecol.
2009 Nov;52(11):1164-1168.
One case of Lynch type II syndrome
- Affiliations
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- 1Department of Obstetrics and Gynecology, Presbyterian Medical center, Jeon-ju, Korea. kyungjin_k@hotmail.com
- 2Department of pathology, Presbyterian Medical center, Jeon-ju, Korea.
Abstract
- Lynch syndrome is also called Hereditary nonpolyposis colorectal cancer (HNPCC). It is characterized by a risk of colorectal cancer and other cancers of the endometrium, ovary, stomach, small intestine etc. The increased risk is due to inherited mutations that impaired DNA mismatch repair. Two to three percentage of colon cancer is caused by Lynch syndrome. A family history of colon cancer occurs at a young age. We experienced one case of Lynch syndrome who had had stomach cancer, endometrial cancer and colon cancer recently. Hence we report this case with a brief review of literature.