Korean J Obes.  2014 Sep;23(3):203-210. 10.7570/kjo.2014.23.3.203.

The Effects of Marathon Running on Retinol Binding Protein 4 and C-reactive Protein Levels in Healthy Middle-aged Korean Men

• Chae J
• Kim S
• Lee J
• Jeon JY

• KMID: 2271131
• DOI: http://doi.org/10.7570/kjo.2014.23.3.203

Abstract

BACKGROUND
The purpose of this study was to investigate the effects of marathon running (42.195 km) on retinol binding protein4 (RBP4) and C-reactive protein (CRP) in healthy middle aged Korean men.
METHODS
Fourteen men aged from 40 to 50 participated in the current study. Eight participants completed marathon running while six participants in the control group took a rest. Blood samples were collected 90 minutes before running the marathon and right after it. Blood samples from the control group were drawn approximately at the same time.
RESULTS
Marathon running (average marathon finishing time: 256.75+/-11.52 min) did not influence plasma levels of RBP4 (pre: 86.63+/-28.87 vs post: 92.22+/-42.20 microg/mL) or CRP (pre: 0.04+/-0.04 vs post: 0.04+/-0.04 mg/dL). After running the marathon, white blood cells increased by 235% (pre: 5.80+/-1.64 th/mm3 vs post: 13.62+/-3.62 th/mm3). Total cholesterol level also increased significantly after marathon running (P<0.05).
CONCLUSION
Marathon running did not affect RBP4 or CRP levels, but it increased WBC level significantly. Further studies are needed to elucidate the exact physiological indicators associated with marathon running, as in WBC, RBP4, and CRP.

Keyword

RBP4; Acute aerobic exercise; Marathon; Middle-aged Korean men

MeSH Terms

C-Reactive Protein*
Carrier Proteins*
Cholesterol
Humans
Leukocytes
Male
Middle Aged
Plasma
Running*
Vitamin A*
C-Reactive Protein
Carrier Proteins
Cholesterol
Vitamin A