Korean J Obes.
2012 Dec;21(4):197-202.
Drug Therapy for Obesity
- Affiliations
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- 1Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea. spark@cha.ac.kr
Abstract
- Obesity is associated with a substantial increase in metabolic disorders and various cancers. As weight loss achieved with lifestyle intervention is modest, there is a need for drug treatment.
Orlistat, phentermine, diethylpropion, phendimetrazine, mazindol have been approved as anti-obesity drugs by Korea Food and Drug Administration. Among these drugs, orlistat is the only approved drug for long-term weight management. The U.S. Food and Drug Administration approved lorcaserin for treatment of obesity in June 2012. Qsymia is a combination of phentermine and topiramate that was approved by USFDA in July 2012. There are currently a large number of drugs for the treatment of obesity undergoing research and development. Drug therapy may play an important role in the treatment of obesity.