Korean J Med.  2014 Sep;87(3):379-382. 10.3904/kjm.2014.87.3.379.

Symmetrical Peripheral Gangrene Complicating Escherichia coli Sepsis Associated with Antiphospholipid Antibodies in Lupus Nephritis

Affiliations
  • 1Department of Internal Medicine, Seoul Red Cross Hospital, Seoul, Korea.
  • 2Department of Pathology, Seoul Red Cross Hospital, Seoul, Korea.
  • 3Division of Public Health Medical Service, Seoul National University Hospital, Seoul University College of Medicine, Seoul, Korea. annie8012@naver.com

Abstract

Antiphospholipid syndrome (APS) is an autoimmune disease that involves vascular thrombosis and pregnancy morbidity associated with elevated titers of antiphospholipid antibodies. APS can affect any organ and has a variety of clinical manifestations. Infections can be associated with thrombotic events in APS, including the potentially fatal subset catastrophic APS. We report a case of extensive symmetrical peripheral gangrene complicating Escherichia coli sepsis associated with antiphospholipid antibodies in a patient with lupus nephritis.

Keyword

Antibodies; Antiphospholipid; Lupus nephritis; Gangrene; Thrombosis

MeSH Terms

Antibodies
Antibodies, Antiphospholipid*
Antiphospholipid Syndrome
Autoimmune Diseases
Escherichia coli*
Gangrene*
Humans
Lupus Nephritis*
Pregnancy
Sepsis*
Thrombosis
Antibodies
Antibodies, Antiphospholipid
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