Korean J Med.
2014 Sep;87(3):379-382. 10.3904/kjm.2014.87.3.379.
Symmetrical Peripheral Gangrene Complicating Escherichia coli Sepsis Associated with Antiphospholipid Antibodies in Lupus Nephritis
- Affiliations
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- 1Department of Internal Medicine, Seoul Red Cross Hospital, Seoul, Korea.
- 2Department of Pathology, Seoul Red Cross Hospital, Seoul, Korea.
- 3Division of Public Health Medical Service, Seoul National University Hospital, Seoul University College of Medicine, Seoul, Korea. annie8012@naver.com
- KMID: 2269254
- DOI: http://doi.org/10.3904/kjm.2014.87.3.379
Abstract
- Antiphospholipid syndrome (APS) is an autoimmune disease that involves vascular thrombosis and pregnancy morbidity associated with elevated titers of antiphospholipid antibodies. APS can affect any organ and has a variety of clinical manifestations. Infections can be associated with thrombotic events in APS, including the potentially fatal subset catastrophic APS. We report a case of extensive symmetrical peripheral gangrene complicating Escherichia coli sepsis associated with antiphospholipid antibodies in a patient with lupus nephritis.
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