Korean J Med.  2015 Jun;88(6):711-714. 10.3904/kjm.2015.88.6.711.

A Case of Tubulointerstitial Nephritis and Uveitis with Fanconi Syndrome

Affiliations
  • 1Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea. zhidao79@naver.com
  • 2Department of Ophthalmology, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea.

Abstract

Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease that comprises 4.7% of acute interstitial nephritis. With reno-ocular manifestations, TINU syndrome is accompanied by symptoms such as fever, fatigue, malaise, anorexia, vomiting, and arthralgia. TINU syndrome is reported mainly in children or adolescent girls, and it is rare in adults. Although TINU syndrome can present with multiple renal tubular defects, Fanconi syndrome characterized by generalized impairment of proximal tubular function, leading to renal glucosuria, hyperuricosuria, hyperphosphaturia, proximal renal tubular acidosis, and kaliuresis leading to hypokalemia, has rarely been described. We report a case of TINU syndrome with Fanconi syndrome in a 46-year-old HLA B27-positive Korean woman.

Keyword

Nephritis, Interstitial; Uveitis; Fanconi syndrome

MeSH Terms

Acidosis, Renal Tubular
Adolescent
Adult
Anorexia
Arthralgia
Child
Fanconi Syndrome*
Fatigue
Female
Fever
Glycosuria, Renal
Humans
Hypokalemia
Hypophosphatemia, Familial
Middle Aged
Nephritis, Interstitial*
Rare Diseases
Uveitis*
Vomiting
Full Text Links
  • KJM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr