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Adult Idiopathic Renal Fanconi Syndrome: A Case Report

Park DJ, Jang KS, Kim GH

Renal Fanconi syndrome (RFS) is caused by generalized proximal tubular dysfunction and can be divided into hereditary and acquired form. Adult-onset RFS is usually associated with drug toxicity or systemic...
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Adefovir-induced Fanconi syndrome associated with osteomalacia

Park S, Kim WI, Cho DH, Kim YJ, Kim HS, Kim JH, Cha SK, Park KS, Lee JH, Lee SM, Lee EY

Fanconi syndrome is a dysfunction of the proximal renal tubules that results in impaired reabsorption and increased urinary loss of phosphate and other solutes. The pathophysiology of drug-induced Fanconi syndrome...
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Three Cases of Osteomalacia with Fractures Induced by Adefovir in Chronic Hepatitis B

Kim AR, Choi YJ, Chung YS

Adefovir dipivoxil is used antiviral agent in the treatment of chronic hepatitis B virus infection. This drug is recommended for patients infected with lamivudine-refractory hepatitis B. Many studies of low-dose...
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Ga68-DOTA Peptide PET/CT to Detect Occult Mesenchymal Tumor-Inducing Osteomalacia: A Case Series of Three Patients

Ho CL

Tumor-induced osteomalacia (TIO) is a rare disease that manifests with paraneoplasic syndrome and overproduction of fibroblast growth factor 23 (FGF23), leading to renal phosphate wasting and hyperphosphaturia, eventually leading to...
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A Case of Tubulointerstitial Nephritis and Uveitis with Fanconi Syndrome

Kim M, Kim HW, Kim JY, Jeong J, Park EJ, Kim J, Kim SM

Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease that comprises 4.7% of acute interstitial nephritis. With reno-ocular manifestations, TINU syndrome is accompanied by symptoms such as fever, fatigue,...
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Phosphaturia as a Promising Predictor of Recurrent Stone Formation in Patients with Urolithiasis

Ha YS, Tchey DU, Kang HW, Kim YJ, Yun SJ, Lee SC, Kim WJ

  • KMID: 2314710
  • Korean J Urol.
  • 2010 Jan;51(1):54-59.
PURPOSE: Recent studies have suggested that renal phosphate leakage and the associated phosphaturia are significant underlying causes of calcium urolithiasis. The aims of this study were to assess whether phosphaturia...
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A Case of Multiple Myeloma with Ameliorated Bone Pain after Treatment of Adult Fanconi Syndrome

Kwon HL, Cho SJ, Song YS, Song HH, Oh JE, Kim SJ, Kim HJ, Noh JW

  • KMID: 2253232
  • Korean J Nephrol.
  • 2008 Jul;27(4):481-486.
Adult Fanconi syndrome is characterized by variable abnormalities caused by renal proximal transport defects, resulting in glycosuria, aminoaciduria, bicarbonaturia, uricosuria and phosphaturia. A 57-year-old man with kappa-light chain multiple myeloma,...
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Two Cases of Oculocerebrorenal Syndrome in Two Brothers Diagnosed after Congenital Cataract Surgery

Suk KW, Lee SJ, Kim WS

  • KMID: 2110359
  • J Korean Ophthalmol Soc.
  • 2006 Sep;47(9):1502-1511.
PURPOSE: We report two cases of brothers diagnosed with oculocerebrorenal syndrome after binocular congenital cataract surgery. METHODS: Two brothers who had undergone surgeries for congenital cataracts showed growth retardation, proteinuria, and...
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Clinical Characteristics of Arthrogryposis, Renal Tubular Dysfunction, Cholestasis(ARC) Syndrome in Korea

Lee SM, Kim JH, Lee JS, Han SJ

  • KMID: 1627747
  • J Korean Soc Pediatr Nephrol.
  • 2005 Oct;9(2):222-230.
PURPOSE: ARC syndrome refers to an association of arthrogryposis, renal tubular dysfunction, and cholestasis. The VPS33B gene was recently identified as the causative gene. So far, 41 cases of ARC...
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Clinical Study of Hypophosphatemic Rickets

Lee CJ, Cho HY, Kang JH, Shin CH, Ha IS, Cheong HI, Yang SW, Choi Y

  • KMID: 2098814
  • J Korean Soc Pediatr Nephrol.
  • 2004 Oct;8(2):195-204.
PURPOSE: Hypophosphatemic rickets is a hereditary disease, characterized by hypophosphatemia due to renal phosphate wasting, impaired renal production of 1,25-dihydroxyvitamin D3, rachitic bone deformities and impaired growth. The purpose of...
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A Case of the Fanconi Syndrome with Nephrocalcinosis

Kim YM, Park SS, Lee JS, Kim SY

  • KMID: 2098804
  • J Korean Soc Pediatr Nephrol.
  • 2003 Oct;7(2):234-238.
Fanconi syndrome is a generalized functional disorder of the proximal tubule of the kidney and is characterized by aminoaciduria, glycosuria, hyperphosphaturia, dehydration, rickets, and growth failure. Nephrocalcinosis and hypercalciuria are...
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A Case of Oncogenic Osteomalacia Caused by Chondromyxoid Fibroma

Oh KW, Kang MI, Lee WY, Lee TK, Chang JH, Suh JP, Cha BY, Lee KW, Son HY, Kang SK, Park JM, Lee KY, Rhee SK, Woo YK

  • KMID: 2199572
  • J Korean Soc Endocrinol.
  • 1999 Dec;14(4):764-770.
Oncogenic osteomalacia is a rare clinicopathological condition. The syndrome is characterized by hypophosphataemic osteomalacia with hyperphosphaturia, low plasma 1,25-dihydroxyvitamin D and normal plasma calcaemia and parathyroid hormone, associated with a...
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A Case of Osteosarcoma induced Oncogenic Osteomalacia Detected by MRI

Lim SK, Song YD, Lee HC, Huh KB, Park KH, Kim KR, Hong SW, Nam JH, Yook JI, Choi BJ, Kim MK, Shin KH

  • KMID: 2199472
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):401-409.
Oncogenic osteomalacia is a syndrome characterized by phosphaturia, hypophosphatemia, decreased 1,25-dihydroxyvitamin D level and specific signs and symptoms of osteomalacia. It is associated with the presence of neoplasm originated from...
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Two Cases of Pseudohypoparathyroidism

Hong DE, Lee YK, Kim DU, Jeong DC, Hur JK, Oh CK, Lee IJ, Lee BC

  • KMID: 2193878
  • J Korean Soc Pediatr Endocrinol.
  • 1998 Nov;3(2):219-227.
Pseudohypoparathyroidism(PHP) is a genetic disorder characterized by target cell resistance to the effect of parathyroid hormone(PTH). The disorder is classified into type I a, I b, I...
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Changes in renal brush-border sodium-dependent transport systems in gentamicin-treated rats

Suhl SY, Ahn DW, Kim KR, Kim JY, Park YS

  • KMID: 2071512
  • Korean J Physiol Pharmacol.
  • 1997 Aug;1(4):403-411.
To elucidate the mechanism of gentamicin induced renal dysfunction, renal functions and activities of various proximal tubular transport systems were studied in gentamicin-treated rats (Fisher 344). Gentamicin nephrotoxicity was induced by injecting gentamicin...
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A case of Fanconi syndrome

Lee YW, Lim IS, Kim CH

  • KMID: 1945955
  • J Korean Pediatr Soc.
  • 1993 May;36(5):737-742.
Fanconi syndrome is a complex of renal tubular dysfunction defined by glycosuria without diabetes, generalized aminoaciduria, phosphaturia, bicarbonaturia, uric aciduria, and renal tubular acidosis. It is often associated with hypokalemia,...
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