Korean J Med.  2013 Aug;85(2):223-228.

A Case of Podostroma Cornu-Damae Intoxication Similar to Drug Hypersensitivity Syndrome

• Yang JN
• Kang JH
• Kang YS
• Seok SJ
• Kim WK

Abstract

The clinical aspects of intoxication can be similar to those of drug hypersensitivity syndrome, including desquamation, hematologic abnormalities, multiple organ failure, and even death. Many people consume mushrooms that they collect in the mountains, and consequently, the incidence of poisonous mushroom intoxication is increasing. Podostroma cornu-damae is a poisonous mushroom not well-known to the public that contains trichothecene, a deadly poison. It is difficult to differentiate P. cornu-damae from other edible mushrooms, especially young Ganoderma lucidum. Therefore, the general public should be aware of the dangers of indiscreet ingestion of mushrooms. When physicians treat patients presenting clinical symptoms similar to those of drug hypersensitivity reaction following the intake of mushrooms, poisonous mushroom intoxication must be taken into consideration. We report this case together with a literature review, as we experienced one P. cornu-damae intoxication case showing similar clinical aspects to drug hypersensitivity syndrome.

Keyword

Drug hypersensitivity syndrome; Intoxication; Mushroom; Podostroma cornu-damae; Trichothecene

MeSH Terms

Abnormalities, Multiple
Agaricales
Drug Hypersensitivity
Eating
Humans
Incidence
Reishi