Arch Plast Surg.  2012 Sep;39(5):497-503. 10.5999/aps.2012.39.5.497.

Reliability of Reconstructed Breast Flap after Chemotherapy and Radiotherapy in Immediate Breast Reconstruction

• Lee KC
• Kim TH
• Park SS
• Kim MS
• Kim MH
• Kim SK
• Cho SH
• Lee MR
• Lee JH
• Lee HS
• Kim DC

• KMID: 2267713
• DOI: http://doi.org/10.5999/aps.2012.39.5.497

Abstract

BACKGROUND
Postmastectomy adjuvant therapy is used to prevent locoregional recurrence and improve overall breast cancer specific survival rates. However, it can adversely affect the cosmetic results of reconstruction. Therefore, the authors examined flap stability and patients' satisfaction with immediate breast reconstruction after adjuvant therapy.
METHODS
We retrospectively reviewed the medical records of 204 patients from January 2006 to November 2011. For complication rates, the authors categorized the patients who underwent the immediate breast reconstruction into 4 groups: adjuvant chemotherapy and radiotherapy group, adjuvant chemotherapy only group, adjuvant radiotherapy only group, and the group that did not undergo adjuvant therapy. For comparison of patients' satisfaction, the study was performed with an additional 16 patients who had undergone delayed breast reconstruction.
RESULTS
Regarding complication rates, the group that had undergone adjuvant therapy showed no significant difference compared to the group that did not undergo adjuvant therapy. In evaluating the patients' satisfaction, there was no significant difference.
CONCLUSIONS
Even after adjuvant therapy, immediate breast reconstruction showed good results with respect to flap stability and patients' satisfaction. Immediate breast reconstruction and adjuvant therapy is a safe and useful option for breast cancer patients.

Keyword

Drug therapy; Radiotherapy; Breast; Surgical flaps

MeSH Terms

Breast
Breast Neoplasms
Chemotherapy, Adjuvant
Cosmetics
Female
Humans
Mammaplasty
Medical Records
Radiotherapy, Adjuvant
Recurrence
Retrospective Studies
Surgical Flaps
Survival Rate
Cosmetics